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Indians should be proud of “India”. We have grown from a tiny group in the “sixties” to what we are today through “IDMA” (Indian Drug Manufacturers’ Association), through intense “networking” and “knowledge exchange” between pharmaceutical and allied p...

It has been established that sulfoxide with sulfones have distinct pharmacological effects. Commodity compounds like sulfoxide and sulfones find widespread use in many chemical disciplines. This is why organic chemists find the synthesis of sulfoxide and sulfones so interesting. In the process of...

2D QSAR has been performed on a series of pyridine carbonitrile and trifluoromethyl phenyl derivatives. 53 compounds were divided into training and test sets out of which 37 compounds generated a final QSAR model. The most significant model with n = 37, r = 0.916, r2 = 0.762, r2 cv = 0.759, s val...

The study was aimed at developing topical gel containing papain as the drug and assessing its antipsoriatic activity. Carbopol was used as the polymer and drug-excipient compatibility was ascertained by infrared spectroscopy (Fourier transform) and differential scanning calorimetry. All prepared ...

The present work deals with extraction, isolation and characterization of phytoconstituents from seeds of Caesalpinia crista Linn and the study of their antiplasmodial activity. The phytoconstituents were extracted using soxhlet apparatus and separated by column chromatography. Structural elucida...

The method of “Inductively Coupled Plasma Mass Spectrometry” (ICP-MS) may be interpreted as a trend in pharmaceutical determination of elemental impurities. The development of a specific process that is precise for all elemental impurities, however, is still a task. The ICP-MS technique using...

A simple, fast and accurate Reverse Phase High Performance Liquid Chromatography method has been established and validated for estimation of rosuvastatin and teneligliptin in their synthetic mixture. The chromatographic separation was achieved on Agilent Inertsil Octa Decyl Silane (ODS) C18 (250 ...

Vrudhadarak rasayan has been prepared in accordance with ayurvedic literature. Specifically, this formulation is based on Vrudhadarak rasayan developed by Chakradatta. The effect of Vrudhadarak rasayan on memory was evaluated using pre-clinical animal table with special reference to retention of ...

A robust HPLC method was developed and validated for the quantitative estimation of furosemide tablet and dissolution testing. The optimization of chromatographic conditions (% organic phase, flow rate and pH of aqueous phase) was done using the Box-Behnken experimental design. The creation of a ...

A simple, precise, accurate, and rapid derivative spectrophotometric approach for the simultaneous quantification of sulfacetamide sodium (SUL) and prednisolone acetate (PRE) in the combined dosage form has been established and validated. The wavelengths selected for analysis are 230 nm (ZCP of S...