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Editorial

NMR FOR “PHARMACY OF THE WORLD”

PAGE 5-6

Dear Reader,

NMR (Nuclear Magnetic Resonance) spectroscopy is widely used to determine structure of potential drug compounds or NCEs. However, the more important and significant use of NMR is in detecting and identifying impurities. Peaks of common organic solvents and solvent excipients ...

Dr. Gopakumar G. Nair

Editor

Indian Drugs

Review Article

PLANT DNA BARCODES: APPLICATION IN HERBAVIGILANCE

PAGE 7-18

Globally, 80% of the world population uses the herbal medicines. Wellbeing is a key guideline in arranging natural prescriptions and herbal products for medical care, and a basic segment of value control. Among consumers, there is a widespread misconception that “natural” always mean ...

Yogesh Murtia,b, Sonia Singha,b, Jyotic and Krishn K. Agrawald*

Original Research Articles

IN SILICO EVALUATION OF PYRAZOLE AND TRIAZINE CONTAINING PYRIDOPYRIMIDINES

PAGE 19-32

Cancer, seen as one of the highly prevelant life endangering diseases today, is mainly associated with the lifestyle led by the population at risk. The superficial observation seen in cancer is the uncontrollable growth and dispersion of abnormal cells. Statistically, the number of patients who ...

Chaithra R. Shettya , Valentina Mendoncaa , Chakrakodi S. Shastryb*, Vidya Murugeshwaria and Walarisa Lamarea

FORMULATION AND IN VITRO EVALUATION OF A NOVEL MEFENAMIC ACID TOPICAL CREAM

PAGE 33-43

Mefenamic acid (MA) is a Non-Steroidal Anti-Inflammatory Drug (NSAID), which has been established in pharmacologic management of musculoskeletal disorders. This study was designed to formulate and conduct an in vitro evaluation of a novel MA topical cream, which would reduce the gastrointestinal ...

Wan Nurfatini I. W. Ahmada , Kai Bin Liewb*, Lokesh B.V.S.c and Shaharuddin A. Rashida

PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF LITSEA GHATICA STEM BARK

PAGE 44-49

Litsea belonging to the family Lauraceae, is among the most diverse genera of evergreen shrubs and trees. Litsea is distributed majorly in the Western Ghats of India. Litsea are traditionally used to treat cold, fever, bruises, insect bites and other diseases. The objective of this study was to ...

Deepika Tiwaria and Tabassum Khanb*

ANALYTICAL METHOD DEVELOPMENT FOR SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN HCL AND OLOPATADINE HCL IN BULK DRUG AND FORMULATION BY RP-HPLC METHOD

PAGE 50-60

A reverse phase chromatography technique to simultaneously estimate ciprofloxacin HCl and olopatadine HCl as bulk drugs and in formulation has been developed. The chromatographic separation of drugs and formulation was accomplished on C18 Agilent Zorbax column (250 x 4.6 mm, 5 µm) using ...

Munira M. Momina and Darakhshan A. Shaikhb*

HPTLC AND FIRST DERIVATIVE UV-SPECTROPHOTOMETRIC METHODS FOR ESTIMATION OF VILAZODONE IN PHARMACEUTICALS

PAGE 61-66

A new HPTLC method and a sensitive UV spectrophotometric method were established for estimating vilazodone hydrochloride in its pharmaceutical formulations. An environment-friendly chromatographic mobile phase consisting of ethyl acetate: toluene: formic acid (5:4:1, V/V/V) along with ultraviolet...

Sagar S. Pandaa * and Ravi Kumar V.V. Beraa

METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF OZENOXACIN IN PHARMACEUTICAL PRODUCTS BY MICROBIOLOGICAL ASSAY

PAGE 67-74

Ozenoxacin is a novel non-fluorinated topical antibiotic belonging to the quinolone family. HPLC techniques are normally used for the quantification of the efficacy of ozenoxacin, however, the HPLC technique is unable to infer bioactivity against microorganisms. The goal of this article was to ...

Piyush Kumara , Prasad Thotaa *, Bhavna Kumaria , Manoj K. Pandeya , Anil K. Teotiaa and Rajeev S. Raghuvanshib

PHARMACODYNAMIC EVALUATION OF DIETARY SUPPLEMENTATION OF AVERRHOA CARAMBOLA FRUIT EXTRACT AGAINST LEAD ACETATE-INDUCED HEPATOTOXICITY IN RATS

PAGE 75-83

Lead is a toxicant that may induce a wide range of social, biochemical, and physiological changes in humans. This study is undertaken to evaluate the pharmacodynamic effects of dietary supplementation of Averrhoa carambola, fruit extract (ACF) against lead acetate-induced hepatotoxicity in rats. ...

Ranjeet Singha , Neetu Sachanb*, Shiv D. Singhc and Phool Chandraa,d

ANTI-HEMORRHOIDAL ACTIVITY OF AYURVEDIC CREAM IN RATS

PAGE 84-88

Piloheal cream is an Ayurvedic proprietary medicine claimed to be effective in the treatment of hemorrhoids. The present work was undertaken to evaluate the anti-hemorrhoidal activity of Piloheal cream against croton oil-induced hemorrhoids in rats. The hemorrhoids were induced by applying 3% ...

Anil T. Pawara *, Chinmay D. Deshmukha , Digambar K. Jadhavb and Ranganath R. Kulkarnib

Short Communications

DEVELOPMENT AND CHARACTERIZATION OF CANDESARTAN NANOCRYSTALS

PAGE 89-90

Nanotechnology is the latest technology employed in pharmaceutical research. Candesartan is an antihypertensive drug belonging to the class of angiotensin II receptor blockers. Candesartan is slightly soluble in water and exists in crystalline form. Candesartan nanocrystals were prepared by the ...

Tripti Joshia , Venkatesh D. Puttegowdaa *, Sailaja L.a , Roopa Karkia and Divakar Golia

EFFECT OF SURFACTANT AND METHODS OF DRYING ON METHOTREXATE HYDROCHLORIDE LOADED CHITOSAN BEADS

PAGE 91-93

To get chitosan beads, an ionotropic gelation technique was used in which drug containing chitosan solution added into tripolyphosphate solution. Obtained beads were evaluated to study the effect of Span 80 and methods of drying on their properties. Air drying method resulted in shrunken beads, ...

Rajendra M. Kotadiyaa *

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