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NMR (Nuclear Magnetic Resonance) spectroscopy is widely used to determine structure of potential drug compounds or NCEs. However, the more important and significant use of NMR is in detecting and identifying impurities. Peaks of common organic solvents and solvent excipients ...

Globally, 80% of the world population uses the herbal medicines. Wellbeing is a key guideline in arranging natural prescriptions and herbal products for medical care, and a basic segment of value control. Among consumers, there is a widespread misconception that “natural” always mean “safe....

Cancer, seen as one of the highly prevelant life endangering diseases today, is mainly associated with the lifestyle led by the population at risk. The superficial observation seen in cancer is the uncontrollable growth and dispersion of abnormal cells. Statistically, the number of patients who r...

Mefenamic acid (MA) is a Non-Steroidal Anti-Inflammatory Drug (NSAID), which has been established in pharmacologic management of musculoskeletal disorders. This study was designed to formulate and conduct an in vitro evaluation of a novel MA topical cream, which would reduce the gastrointestinal ...

Litsea belonging to the family Lauraceae, is among the most diverse genera of evergreen shrubs and trees. Litsea is distributed majorly in the Western Ghats of India. Litsea are traditionally used to treat cold, fever, bruises, insect bites and other diseases. The objective of this study was to u...

A reverse phase chromatography technique to simultaneously estimate ciprofloxacin HCl and olopatadine HCl as bulk drugs and in formulation has been developed. The chromatographic separation of drugs and formulation was accomplished on C18 Agilent Zorbax column (250 x 4.6 mm, 5 µm) using acetonit...

A new HPTLC method and a sensitive UV spectrophotometric method were established for estimating vilazodone hydrochloride in its pharmaceutical formulations. An environment-friendly chromatographic mobile phase consisting of ethyl acetate: toluene: formic acid (5:4:1, V/V/V) along with ultraviolet...

Ozenoxacin is a novel non-fluorinated topical antibiotic belonging to the quinolone family. HPLC techniques are normally used for the quantification of the efficacy of ozenoxacin, however, the HPLC technique is unable to infer bioactivity against microorganisms. The goal of this article was to au...

Lead is a toxicant that may induce a wide range of social, biochemical, and physiological changes in humans. This study is undertaken to evaluate the pharmacodynamic effects of dietary supplementation of Averrhoa carambola, fruit extract (ACF) against lead acetate-induced hepatotoxicity in rats. ...

Piloheal cream is an Ayurvedic proprietary medicine claimed to be effective in the treatment of hemorrhoids. The present work was undertaken to evaluate the anti-hemorrhoidal activity of Piloheal cream against croton oil-induced hemorrhoids in rats. The hemorrhoids were induced by applying 3% cro...

Nanotechnology is the latest technology employed in pharmaceutical research. Candesartan is an antihypertensive drug belonging to the class of angiotensin II receptor blockers. Candesartan is slightly soluble in water and exists in crystalline form. Candesartan nanocrystals were prepared by the n...

To get chitosan beads, an ionotropic gelation technique was used in which drug containing chitosan solution added into tripolyphosphate solution. Obtained beads were evaluated to study the effect of Span 80 and methods of drying on their properties. Air drying method resulted in shrunken beads, t...