Dear Reader,

The global innovation index 2021 ranked INDIA 48th among 131 countries. This low ranking assigned to India reflects the quality of our research programs. In the realm of pharmaceuticals, the Indian industry has excelled in the manufacture of low value generic products, howeve...

Central nervous system (CNS) is always an area of thrust where continuous efforts are required to achieve targeted drug delivery. The blood brain barrier (BBB) is the chief interfering element in the development of effective neurotherapeutics and efficient drug delivery to the CNS. Large neutral ...

A new series of thiazolidin-4-ones (T1-10) were synthesized by the reaction of Schiff’s bases(Ta-j) and thioglycolic acid in dioxane medium in the presence of anhydrous zinc chloride as a catalyst. All the newly synthesized compounds were characterized by IR, ¹H-NMR and mass spectral...

Lansoprazole has a short half-life and it gets absorbed only in the proximal part of the small intestine. Floating microspheres of such a drug floats on the stomach contents and releases the drug slowly for longer periods of time. Thus, to overcome the problem like short half-life and to enhance ...

The medicinal plant Morinda tinctoria Roxb. is used in the treatment of various diseases traditionally. Report on bioactive evaluation of M. tinctoria Roxb. has led us to the phytochemical examination of M. tinctoria leaves. Our objective was to isolate compounds form M...

A simple, precise and robust UPLC-Q-TOF-MS method was developed for the quantification of four marker compounds, namely citric acid derivative, iso garcinol, garcinol and garcimultiflorone-A in Garcinia morella, in order to study the fragmentation pathways of four marker compounds. The d...

A Reverse Phase High Performance Liquid Chromatographic method was developed and validated for the simultaneous estimation of lornoxicam and tolperisone hydrochloride in bulk drug and its combined dosage form. Chromatographic separation was carried out isocratically by reverse phase water enable ...

The main aim of this study was to assess the possibility of potential interaction of repaglinide and rosiglitazone with diltiazem. A calcium channel blocker, diltiazem potentially inhibits CYP3A4 and 2C8. Important to note, both drugs meglitinide and thiazolidinediones are actively metabolised by...

Cosmetics are composed of a mixture of chemicals and natural compounds, and most adverse effects occur due to sharing the same products and using the makeup after the expiry date. This behavior tends to increase the side effects of cosmetics due to pathogenic infections. Lack of awareness and kno...

Adhatoda vasica is a medicinal plant in use since ancient times. It is a recommended bronchodilator and thus useful in the treatment of asthma. In the present research work, GC/MS analysis of volatile oil isolated from leaves and flowers of A. vasica was carried out. It...

The aim of the present study was to apply combined mixture design to optimize extraction solvent composition to enhance filtration volume and recovery of assay test sample with ethyl cellulose coated tablets. Solvent composition, centrifugation time and additional filtration step were evaluated a...