Polyethylene glycol-ylation (PEGylation) is a phenomenon of modification of a protein, peptide, or non-peptide molecule by linking of one or more polyethylene glycol chains. These synthetic polymers have received FDA approval for internal use. It is an effective metho...

A simple and accurate high performance thin layer chromatographic (HPLTC) method have been developed and validated as per ICH guidelines for estimation of Ofloxacin (OFL) and Ornidazole (ORN) in combined dosage form. The mobile phase was acetone : water : toluene : tr...

Abrus precatorius belongs to the family Fabaceae and is a slender woody perennial climber. The genus Abrus is native to India, introduced to warmer regions of the world. It has gained scientific importance as a potential herbal remedy in treatment of chronic ...

The effect of various concentrations of chitosan as a polymer was investigated for the transdermal delivery of atenolol across human cadaver skin by using dimethylsulfoxide as a penetration enhancer. Atenolol-chitosan matrix type patches were formulated using differen...

The present research work was aimed to develop nasal mucoadhesive microspheres of chlorpheniramine maleate (CPM) & to compare its permeation rate through sheep nasal mucosa and cellulose acetate membrane. The impact of different concentrations of polymer and the dispersion media were evaluate...

A simple, accurate, precise, rapid, economical UV spectrophotometry method, dual wavelength spectrophotometry, has been developed and validated for estimation of Indapamide (IND) and Amlodipine besylate (AML) in combined tablet dosage form and can be used in routine a...

UV spectrophotometric method has been developed for the estimation of deflazacort in pure and its pharmaceutical formulations. In UV method deflazacort showed absorption maximum at 242.8nm in methanol medium and it obeys Beers law in the concentration range of 5-25µg...