Dear Reader,
I have followed the progress of Indian Drugs for more than three decades, and have the privilege of being on its editorial board for the last many years. Currently, the journal is in its 55th year, since its inception in 1963. There are many stalwarts, many of them still living,...

Quantitative Structure-Activity Relationship studies were performed for correlating the imidazolyl derivatives and their activity using molecular modeling studies. The statistically significant best 2D model was having correlation coefficient = 0.8221 and cross-validated squared correlation coeff...

The objective of the present study was to develop nano range liposomal formulation for cancer therapy and optimize the formulation by response surface method, i.e. 3² factorial design, in order to minimize more efforts, time and material use when formulation like the liposomes are deve...

Bioactive principles from the hyroalcoholic (50%) extract of Ficus racemosa L. bark were isolated and characterized to evaluate antifertility activity in female albino rats. Oral acute toxicity study was done with crude extract for 24h. The hydro alcoholic extract of F. racemosa...

Fluconazole (anhydrate) is an anti-fungal agent which exists in various polymorphic forms. The present study is an attempt to obtain crystal solvates of fluconazole using various solvents and study its effect on polymorphic transformation and its implication on solubility and dissolution. flucona...

A simple, accurate and precise HPTLC method has been developed for the estimation of rutin from the aerial parts of Alhagi pseudalhagi (M. Bieb) Desv. The method employed silica gel 60 F₂₅₄ precoated plates as stationary phase and a mixture of ethyl acetate: acetic acid: formic acid: w...

3-Acetamidobenzene -1, 2-dicarboxylic acid is a potential genotoxic impurity which gets formed during synthesis of 3- acetamidopthalic anhydride, a Key Starting Material (KSM) for manufacturing of apremilast API. During handling upon exposure to moisture, the anhydride ring of KSM 3-acetamidoptha...

The study was caried out with the intention to bring out the biological prospective nature of the marine halophyte Salicornia europaea L. The bioactive phytochemicals of the halophyte were extracted. The chemicals in the crude extract were evaluated for cytotoxic activity against MCF7 ce...

Shatapaki Ksheerbala Taila (SKT) is a herbal formulation in oil form which is used for treating central nervous system disorders, rheumatism and insomnia. The current study was conducted in Wistar rats for evaluating the effect of Shatapaki Ksheerbala Taila (SKT) on Central Nervous System (CNS). ...

A simple, accurate, precise, reproducible and economical UV spectroscopic method for simultaneous estimation of Rosuvastatin calcium and Hydrochlorthiazide in marketed formulation has been developed. Method employs solving of simultaneous equations based on the measurement of absorbance at two wa...

A simple precise and rapid Reverse Phase High Performance Liquid Chromatographic method has been developed for quantitative determination of antineoplastic drug bexarotene and its capsule formulation. In this method Synchronis (C18, 25cm×4.6mm id , 5μ) column with mobile phase consisting of buf...