Table of Contents

May  2018

  • Volume 55
  • Issue 05
  • Page Nos. 80

ISSN: 0019-462X (print)

Guest Editorial

INDIAN DRUGS: TRANSFORMING FOR THE FUTURE

PAGE 5-6

Dear Reader,
I have followed the progress of Indian Drugs for more than three decades, and have the privilege of being on its editorial board for the last many years. Currently, the journal is in its 55th year, since its inception in 1963. There are many stalwarts, many of them still living,...

Dr. Saranjit Singh

Original Research Articles

Development of a Credible QSAR and k Nearest Neighbor models for Imidazolyl derivatives

PAGE 7-13

Quantitative Structure-Activity Relationship studies were performed for correlating the imidazolyl derivatives and their activity using molecular modeling studies. The statistically significant best 2D model was having correlation coefficient = 0.8221 and cross-validated squared correlation coeff...

Sharma M. C.a*

 

DEVELOPMENT AND OPTIMIZATION OF LIPSOMAL DRUG DELIVERY SYSTEM BY 32 FACTORIAL DESIGN FOR CANCER THERAPY

PAGE 14-24

The objective of the present study was to develop nano range liposomal formulation for cancer therapy and optimize the formulation by response surface method, i.e. 32 factorial design, in order to minimize more efforts, time and material use when formulation like the liposomes are deve...

Bangale G. S.a*, Rajesh K. S.b and Shinde G.V.c

ISOLATION, CHARACTERIZATION AND ANTIFERTILITY ACTIVITY OF THE ACTIVE MOIETY FROM THE BARK OF FICUS RACEMOSA L.

PAGE 25-30

Bioactive principles from the hyroalcoholic (50%) extract of Ficus racemosa L. bark were isolated and characterized to evaluate antifertility activity in female albino rats. Oral acute toxicity study was done with crude extract for 24h. The hydro alcoholic extract of F. racemosa...

Soni V.a*, Jha A. K.b, Dwivedi J.C and Soni P.a

POLYMORPHIC STUDIES OF FLUCONAZOLE IN DIFFERENT CRYSTAL SOLVATE FORMS AND ITS IMPLICATION ON BCS SOLUBILITY AND DISSOLUTION

PAGE 31-36

Fluconazole (anhydrate) is an anti-fungal agent which exists in various polymorphic forms. The present study is an attempt to obtain crystal solvates of fluconazole using various solvents and study its effect on polymorphic transformation and its implication on solubility and dissolution. flucona...

Walvekar P. M.a*

Development and validation of high-performance thin-layer chromatographic method for the determination of Rutin from the aerial parts of Alhagi pseudalhagi (M. Bieb) Desv

PAGE 37-41

A simple, accurate and precise HPTLC method has been developed for the estimation of rutin from the aerial parts of Alhagi pseudalhagi (M. Bieb) Desv. The method employed silica gel 60 F254 precoated plates as stationary phase and a mixture of ethyl acetate: acetic acid: formic acid: w...

Mishra S. B.a, Singh S.a* and Mukerjee A.a

A novel HPLC method for estimation of genotoxic impurity 3-Acetamidobenzene 1, 2 dicarboxylic acid in key starting material 3-Acetamidopthalic anhydride of Apremilast API

PAGE 42-46

3-Acetamidobenzene -1, 2-dicarboxylic acid is a potential genotoxic impurity which gets formed during synthesis of 3- acetamidopthalic anhydride, a Key Starting Material (KSM) for manufacturing of apremilast API. During handling upon exposure to moisture, the anhydride ring of KSM 3-acetamidoptha...

Shinde P.a*, Shirke S.a, Dwivedi R.a and Dhuppad U.a

Bioprospecting of marine halophyte Salicornia europaea L. and evaluation of its biological potential with special reference to anticancer activity

PAGE 47-56

The study was caried out with the intention to bring out the biological prospective nature of the marine halophyte Salicornia europaea L. The bioactive phytochemicals of the halophyte were extracted. The chemicals in the crude extract were evaluated for cytotoxic activity against MCF7 ce...

Samuel P.a*, J. Vijaya Kumara, Selvarathinam T.a, R. Deena dhayalana and K. Amirtharaja

Effect of Shatapaki ksheerbala Taila on behavior of Albino Wistar rats

PAGE 57-62

Shatapaki Ksheerbala Taila (SKT) is a herbal formulation in oil form which is used for treating central nervous system disorders, rheumatism and insomnia. The current study was conducted in Wistar rats for evaluating the effect of Shatapaki Ksheerbala Taila (SKT) on Central Nervous System (CNS). ...

Bhogate P. S.a*, Sathe N. S.b and Sherikar A. A.c

Short Notes

UV spectrophotometric method for simultaneous estimation of Rosuvastatin calcium and Hydrochlorthiazide in their combined dosage forms

PAGE 63-66

A simple, accurate, precise, reproducible and economical UV spectroscopic method for simultaneous estimation of Rosuvastatin calcium and Hydrochlorthiazide in marketed formulation has been developed. Method employs solving of simultaneous equations based on the measurement of absorbance at two wa...

Sheth A.a*, Patel C. N.a and Shah N. J.a

Reverse Phase High Performance Liquid Chromatographic method for determination of Bexarotene in capsule dosage form

PAGE 67-71

A simple precise and rapid Reverse Phase High Performance Liquid Chromatographic method has been developed for quantitative determination of antineoplastic drug bexarotene and its capsule formulation. In this method Synchronis (C18, 25cm×4.6mm id , 5μ) column with mobile phase consisting of buf...

Dhanvijay N.a*, Munipalli Vijaya Kumara, Patel M.a, Ghani S.a, Singh R. M.a, Nayak S.b and Bhaskar V.b

Current Issue
January 2025
Quick Contact