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The Pharmaceutical industry is the most controlled industry and remains on top of the list with the most regulatory controls through multiple Acts and Rules. Many of the regulations are specific to Pharmaceuticals industry among other governing all others industries, in gener...

Arundo donax L. belongs to the family Poaceae. It has been found in the Mediterranean, North Africa, India and Pakistan. It grows in hilly locations in India. It grows up to 2100-2440 m in the Himalayas. Commonly, A. donax L. is known as Giant Reed in English and Narakata in Hindi. Traditionally ...

In the present study, a series of 5’-(substituted aryl)-2-furanyl}-3,4-dihydro-1H-pyrimidine-2-ones has been designed and synthesized with Beginelli reaction derivatives carried out from the reaction of ethyl acetoacetate 1 with substituted ureas 2 and substituted aryl furfuraldehydes 3 in pres...

The current research work was aimed at improving the solubility of dolutegravir sodium (BCS class II) by utilizing the approach of co-crystallization and formulating orodispersible tablets of chosen cocrystals to maximize the therapeutic use of dolutegravir sodium. Co-crystals were prepared by th...

Ziziphus rugosa Lam. a member of the Rhamnaceae family, is found in the semi-evergreen forests of the Western Ghat region, India. This plant is used in many traditional formulations owing to its benefits in miscarriage, misconception, syphilis, tachycardia, diarrhea, flatulence, dropsy, skin dise...

A colorimetric method for the analysis of dolutegravir in pure form and in tablets has been developed based on the formation of green colour complex. The method is based on the diazotization of carbonyl group and coupling with 3-methyl-2-benzothiazolinone hydrazone reagent in presence of ferric c...

Evaluation of polymorphism for active ingredients and its stability during manufacturing and storage is a critical task for pharmaceutical firms. For solubility enhancement of ritonavir, hot melt extrusion process was selected through conversion of commercially available crystalline form to amorp...

Favipiravir (6-fluoro-3-hydroxy-2-pyrazine carboxamide) is an antiviral drug that specifically and potently inhibits the RNA-dependent RNA polymerase enzyme of RNA viruses. A straightforward stabilityindicating high-performance liquid chromatography (RP-HPLC) approach can be used to identify favi...

The present research work was carried out to evaluate the anti-arthritic activity of ethanolic extract of leaves of Citrus aurantium Linn. on Complete Freund’s adjuvant (CFA)-induced arthritis model in rats. Dried leaves powder was extracted and coded as ECA (ethanolic extract of C. aurantium)....

Mitochondrial dysfunction as a virtue of oxidative stress leads to neurodegeneration. The neurotoxin rotenone, is widely used to induce mitochondrial dysfunction and hence evaluate the neuroprotective action of a sample drug. For this study and comparison, the hexane extract, chloroform extract, ...