Table of Contents

August  2022

  • Volume 59
  • Issue 8
  • Page Nos. 92

Editorial

INNOVATION AND PATENTS RECEIVING THE GOVERNMENT'S ATTENTION

PAGE 5-6

Dear Reader,

Inaugurating the Grand Finale of the Smart India Hackathon, 2022 and addressing the 15000 finalists of the Hackathon, the Honourable Prime Minister of India, Shri Narendra Modi made a clarion call for research and innovation and appealed to make innovation a "way of living" w...

Dr. Gopkakumar G. Nair

Editor

Indian Drugs

Review Article

CHRONIC KIDNEY DISEASES: AN OVERVIEW OF MANAGEMENT AND TREATMENT STRATEGIES

PAGE 7-20

Chronic kidney diseases (CKD) are an important public health concern worldwide. In developed as well in less-developed countries, prevalence of CKD is increasing day by day. Large numbers of people are affected by cost of care, dialysis and transplantation treatment strategies and lack of awarene...

Harshad S. Kaparea *, Sohan S. Chitlangeb, Kaveri S. Aherb and Dheeraj H. Nagorec

Original Research Articles

SYNTHESIS OF SOME NEWER THIAZOLIDINONYL QUINAZOLINONES AND AZETIDINONYL QUINAZOLINONES AS POTENT ANTI-INFLAMMATORY AGENTS

PAGE 21-30

3-Substitutedphenyl-2-bromomethyl-6-substituted quinazolin-4(3H)-ones (7-10) were treated with hydrazine hydrate to give 3-substitutedphenyl-2-hydrazinomethyl-6-substituted quinazolin-4(3H)-ones (11-14). Compounds 11-14 were condensed with various aldehydes to afford 2-substitutedbenzylidene hydr...

Nancya , Sakshi Chaudharyb and Archanaa *

DEVELOPMENT AND EVALUATION OF CAPTOPRIL CONTROLLED RELEASE FLOATING MICROBALLOONS

PAGE 31-38

The objective of the present study was to develop floating microballoons of captopril in order to achieve an extended gastric retention in the upper GIT which may enhance the absorption and improve bioavailability. The floating microballoons were formulated with calcium silicate as porous carrier...

Sasidhar R. Lankapallia *, Vidyadhara Suryadevaraa , Sowjanya L. Battulaa and Ramu Annea

PHARMACOGNOSTIC EVALUATION AND PHYSICOCHEMICAL ANALYSIS OF CAESALPINIA BONDUCELLA IN MASHI KALPANA

PAGE 39-42

Ayurveda has a rich treasure of medical preparations and formulations. The scientific procedures of drug preparations have specific action, site and mode of action. Mashi kalpana is one of the drug preparation methods explained in Ayurveda. This study aims to find the difference between Latakaran...

Usharani S. Sanua * and Sunil S. Vernekarb

RP-HPLC METHOD FOR SIMULTANEOUS QUANTIFICATION OF BERBERINE CHLORIDE AND GALANGIN IN TINOSPORA CORDIFOLIA M. AND ALPINIA GALANGA L. AND THEIR FORMULATIONS

PAGE 43-48

Berberine chloride is a quaternary ammonium compound obtained from Tinospora cordifolia M. and galangin is a member of the flavonol class of flavonoids from Alpinia galanga L. They are reported to have various pharmacological activities. The separation was carried out by using Hypersil BDS 100 RP...

Rajendra K. Patela * and Priti D. Trivedia

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR DETERMINATION OF NORTRIPTYLINE HYDROCHLORIDE IN BULK AND DOSAGE FORM

PAGE 49-52

The present work reports a validated reverse phase-HPLC method for determination of nortriptyline hydrochloride (NORH) in bulk and in its pharmaceutical dosage form. Chromatographic separation was performed on Waters C-18, (250×4.6mm, 5µm) stationary phase using a mixture of 50 mM KH2 PO4 pH 3....

Atul Sherjea * and Sneha Diasa

KNOWLEDGE AND ATTITUDE OF ANTIBIOTIC PRESCRIPTION AMONG IMPLANTOLOGISTS: AN OBSERVATIONAL STUDY

PAGE 53-57

This article discusses the knowledge and attitude of antibiotic prescription among implantologists performing implant surgery and how we contribute to over prescription of antibiotics. Antimicrobial resistance is a substantial catastrophic threat to International Public Health. Antibiotic-resista...

Shalini K.a *, Vidushi S.a and Nisha Y. a

APPLICABILITY OF COMPREHENSIVE MOBILE PHASE IN VALIDATED BIO ANALYTICAL QUANTITATIVE ESTIMATION OF ROSUVASTATIN, EZETIMIBE, AMLODIPINE, VALSARTAN, LERCANIDIPINE AND FLUVASTATIN IN HUMAN PLASMA BY RP-HPLC METHOD

PAGE 58-69

A bio analytical method was developed with compatible mobile phase for estimation of drugs viz. rosuvastatin and ezetimibe, amlodipine and valsartan, lercanidipine and fluvastatin in human plasma. Liquid chromatographic system takes ample of time to stabilise and to attain equilibrium on changeov...

Gurappa K. Dyadea * and Ramesh L. Sawantb

IN VITRO MICROPROPAGATION OF ENDEMIC TAXON CURCUMA KARNATAKENSIS AND STUDY OF ITS ANTIBACTERIAL ACTIVITY

PAGE 70-73

Micropropagation is the true-to-type propagation of a selected genotype using in vitro culture techniques. Curcuma karnatakensis is a small herb endemic to Karnataka and belongs to the Zingiberaceae family. C. karnatakensis, with its small distribution area in Karnataka, is prone to any kind of t...

Ravikiran S.a *, Sujani K.a , Anitha S.a and Manjunath N.a

Short Communications

FORMULATION AND EVALUATION OF COSMETIC PREPARATIONS USING NOVEL NATURAL COLORANT FROM LANTANA CAMARA LINN (CHATURANGI) AND BOMBAX CEIBA LINN (SHAALMALI)

PAGE 74-77

The present work aimed to formulate various cosmetic formulations comprising of extract of Lantana camara Linn. and Bombax ceiba Linn. as natural coloring agents. Dried and powdered leaves of L. camara Linn and dried thorn powder of B. ceiba Linn produce red color. The obtained color was used as ...

Dheeraj S. Randivea *, Somnath D. Bhingeb, Mangesh A. Bhutkara , Kiran P.Shejawala , Anjum S. Mullaa , Monika S. Thorata and Pranoti D.Patila

COMPARATIVE EVALUATION OF AYURVEDIC FORMULATION SITOPLADI CHURNA OF DIFFERENT BRANDS

PAGE 78-81

In ayurvedic system of treatment, churnas are as good as are asavas and arishtas for the eradication of diseases. As a part of evaluation, Dabur and Baidhyanath brands properties of Sitopladi churna were tested for relevant organoleptic, physiochemical, micromeretics and fluorescence properties. ...

Vishal Sonia * and Priyanka Sonia

NARINGENIN LOADED CYCLODEXTRIN NANOPARTICLES FOR IMPROVED DRUG DELIVERY

PAGE 82-85

Herbal drug naringenin is well known for its anti-cancer, anti-oxidant, anti-inflammatory activities, as carbohydrate metabolism promoter, immunity system modulator, BCRP/ABCG2 inhibitor, hormone substitute and hormone antagonist since decades. However, use of naringenin as pharmaceutical aid is ...

Lokesh Adhikaria , Nitin Kumara , Abhijit Sahab, Ajay Semaltya and Mona Semaltya *

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