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Many bills and proposals are being mooted and moved by the present Government in response to public representations and also to resolve internal constraints and for operational reasons. Regulatory aspects are closely linked to research and innovation. However, the Indian rese...

Tuberculosis remains a major threat to mankind, becoming more deadly due to COVID-19 pandemic. The worldwide scenario is daunted by additional factors such as drug resistance, non-adherence and complexity of the treatment. To overcome these obstacles, there is a constant need for novel drug devel...

Benzoic acid substituted imidazo[2,1-b][1,3,4]thiadiazoles were synthesized using appropriate reaction scheme. The synthesized derivatives were then purified and elucidated for their structure by measuring their melting points, infra-red spectra and proton NMR spectra. The progress of the reactio...

Considerable evidence that drug bioavailability is influenced by food, in conjunction with the poor and erratic bioavailability of sparingly soluble drugs, serve as a stimulus in the research field for examining new formulations that may provide more consistent absorption. The in vitro a...

Despite the long history of traditionally used and clinically potential plant Anacyclus pyrethrum (Akarkara; family – Asteraceae) root parts, the plant has never been investigated systematically for the scientific phytochemical and biological studies till date. Thus, present investigation was e...

The present work describes a simple, accurate and validated UV spectrophotometric method for determination of trans-resveratrol loaded in ethosomal formulation. The method was validated for different parameters like linearity, precision, specificity, accuracy, limit of detection (LOD), limit of q...

A rapid, precise, robust, and selective HPTLC technique has been developed for the simultaneous estimation of ellagic acid and berberine from a marketed polyherbal formulation. Chromatographic separation was performed over pre-coated silica gel TLC plates, via a linear ascending technique using t...

In the present study effort has been made to establish the antiulcer activity of Saraca asoca (Roxb.), De Wild (family-Caesalpinaceae) stem bark hydroalcoholic-extract using ethanol induced ulceration model in albino rats, because no systematic study has been reported for its antiulcer activity. ...

This experiment aims to develop and validate the RP-HPLC method for clofarabine in a bulk and pharmaceutical dosage form. Chromatographic separation was achieved on Inertsil ODS 3V (150× 4.6 mn) diameter column. The mobile phase comprised of phosphate buffer (pH 4.0): methanol (40:60) at a flow ...

Liquisolid technique is an emerging technology of formulation development. In the present work, a modified-release formulation of gliclazide was developed by using the liquisolid technique. Gliclazide was dispersed in a nonvolatile solvents system of Tween 80 and propylene glycol, followed by ads...