Amorphous pharmaceutical solids have recently attracted the interest of pharmaceutical scientists because of a continuous increase in the number of developmental drug molecules that are insoluble. Amorphous state of the drug provides several pharmacokinetic advantages...
A simple, fast, precise and accurate ultra high performance liquid chromatography method was developed for degradation study of eletriptan hydrobromide (EH) under exaggerated conditions. An Inertsil ODS C18 (250 x 4.6 mm, 5µm) column in isocratic mode was used with m...
Skin penetration of a drug and the effect of formulation additives can be evaluated by performing diffusion studies. In the present study semisolid cream formulation comprising of bacteriostatic antibiotic of 2 different creams have been compared for the penetration o...
The objective of the present study was to develop quality parameters to evaluate and standardize the polyherbal formulation and also to study the eight crude drugs viz. Curcuma longa - rhizome (Manjal), Salacia oblonga- root bark (Ekanayakam), Em...
Lercanidipine hydrochloride, an anti hypertension drug, undergoes extensive first pass metabolism to inactive metabolites leading to very poor oral bioavailability. To overcome this problem, buccal films of Lercanidipine hydrochloride were prepared by solvent casting ...
Ethanol (Direct) extracts of mangrove plants, namely, Avicennia officinalis Linn. and Rhizophora mucronata Lam. were included for the present in vitro study. Pepsin was used as a substitute for HIV-protease to evaluate inhibitory activity of these ex...
Mayur Puccha Bhasma(calx of peacock feather), an unique animal product used traditionally in the management of Chardhi (vomiting), Hikka (hiccough), Swasa (respiratory disorder) was prepared according to the prescr...
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