In recent years there have been several scientific and technological advancements in the research and development of rate-controlled oral drug delivery systems by overcoming physiological adversities,such as short gastric residence time (GRT) and unpredictable gastric...
A high performance thin layer chromatographic method has been developed for the simultaneous determination of olmesartan medoximil and metoprolol succinate from tablet dosage form. The mobile phase consisting of water-methanol-ammonium sulphate (4.5:4.5:1.5 v/v/v) and...
Anti-arthritic activity of Rumalaya Forte (RF), a polyherbal formulation was evaluated by in vivo Complete Freunds Adjuvant induced arthritis animal model in rats. RF 80 mg/kg and 160 mg/kg offered significant anti-inflammatory activity by inhibiting primary ...
Mutual prodrug was synthesized by esterifying diclofenac with paracetamol. In vitro hydrolysis of prodrug in HCl buffer (pH 1.2) and phosphate buffer (pH 7.4) showed that the drug was released more in pH 7.4. The purity of the prodrug was confirmed by TLC and characte...
Earlier researchers have reported the presence of several sesquiterpenoids, chromones and alkaloids. In the present investigation isolation and characterization of a flavone namely apigenin-4, 7-dimethyl ether for the first time from the wood of Aquilaria agallocha Roxb.
...The fruits of Momordica dioica Roxb. ex Wild. & Momordica charantia L. (Cucurbitaceae) are used as vegetable in India. The fruits are used in the management of diabetes and other diseases. Since these effects may be correlated with the presence of anti-oxidant compounds, methanol and 70% acet...
Proteases find wide application in textile, leather, food and pharmaceutical industries. Also this enzyme has considerable therapeutic importance in treating inflammation, digestive and vascular conditions. A protease obtained from a fungal isolate, Aspergillus ni...