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The Hathi Committee Report of 1975 on the Drugs & Pharmaceutical Industry, running into 278 pages, was widely discussed in India, both inside and outside Parliament, as well as in many other countries across the globe. The Hathi Committee Report was never implemented in Indi...

Tremendous research is going on in the field of preparing low calorie diet for diabetes, obesity, hyper-tension, and heart disease, providing potential area for growth to the food and pharmaceutical industry. Dosage forms prepared for diabetic patients lack sucrose as breakdowns into glucose and ...

In continuation of the previous work based upon pyrazoline derivatives having cytotoxic activity, twen-ty-one 1,3,5-substituted pyrazoline derivatives were designed taking into consideration the important functional groups of methisazone, sorafenib and chalcone. the designed derivatives were scre...

Bacteria are becoming more and more resistant to β-lactam antibiotics. One approach to lower such resistance involves combining inhibitors of β-lactamase with β-lactams antibiotics. As such, the need for innovative inhibitors of β-lactamases is urgent. therefore, the aim of this research was ...

The use of microemulsion as a delivery system for improving take-up across the nasal mucosa is cur-rently being studied. A mucoadhesive polymer is added to help extend the retention time on the mucosa.The primary goal of the current research was to create a nano-formulation of amisulpride with th...

Etoposide is a well-known anti-tumor agent used to treat a variety of cancers. Although it is a BCS class IV drug, applications are restricted due to poor solubility and bioavailability. Hence, the current research was designed to overcome these pitfalls. A total of 16 formulation batches were de...

Nature has always been a source of drug candidates. Since ancient times, people have been using plants and their metabolites for various medicinal purposes. Glaucarubinone is a quassinoid present in the family Simaroubaceae. Simarouba glauca, also known as Laxmitaru or paradise tree is grouped un...

In the present study, analytical UV and Rp-HpLC methods for repaglinide were developed for tablet formulation. UV method shows linearity in the range of 10-30 μg mL-1 with a relative coefficient of 0.9999. Linearity is shown in HpLC method in the range of 10- 30 μg mL-1 with a relative coeffici...

The aim of this study was to verify the ability of the UV spectrophotometric method for the simultaneous determination of emtricitabine and tenofovir disoproxil fumarate in tablet dosage form using the principal Component Regression (pCR) and partial Least Squares (pLS) multivariate calibration m...

The present study was conducted on timolol maleate (a non-selective beta-blocker) using in vitro assays and in vivo models of rats. It was tested for its anti-inflammatory activity at three dose levels (1.028 mg kg-1 , 5.14 mg kg -1 and 10.28 mg kg -1). Furthermore, the investigation was supporte...

Amlodipine is a BCS (biopharmaceutical Classification System) class I drug with high permeability and high solubility. It has a long half-life of 30-50h. It is a suitable model drug for formulating orodispersive tablets, as the orodispersive tablets can release the drug immediately. thus, formula...