Table of Contents

September  2014

  • Volume 51
  • Issue 09
  • Page Nos. 1-39

Review Article

Diabetes-Post-Translational Protein Modification for Development of New Drugs

PAGE 5-11

Diabetes is a disorder associated with improper use of glucose by the body leading to increased level of glucose in the blood stream. Beta cells in the pancreas produce the hormone insulin, which is responsible for the movement of glucose into cells where it is utilized to produce energy. Due to ...

Menon P and Kumar M S*

Original Research Articles

Bioanalytical Method Development and Validation of Memantine Hydrochloride by Spectrofluorimetric Method Using OPA β-Mercaptoethanol as Derivatizing Agent

PAGE 12-16

A new, simple, accurate, sensitive and specific bioanalytical spectrofluorimetric method was developed and validated for estimation of memantine hydrochloride (MEM) in human plasma. Estimation of MEM in human plasma was done by spiked human plasma studies. Extraction of MEM from human plasma was ...

Patel C. B., Kothari C. S.*, Patel N. R. and Sherikar O

Development and Characterization of Novel Site Specific Floating-Mucoadhesive Tablets Bearing 5-Flourouracil for Stomach Targeting.

PAGE 23-30

Object of present investigation was to develop and characterize such a gastroretentive tablet, which provides the synergism effect of adhesiveness and floating property for prolonged release of 5-flourouracil within the stomach. The floating mucoadhesive tablets were prepared by the wet granulati...

Bhardwaj P*, Singh R and Swarup A

Simultaneous Estimation and Validation of Ramipril and Telmisartan by UV Spectrophotometry

PAGE 31-35

A simple and sensitive spectrophotometric method for the determination of ramipril and telmisartan in pharmaceutical dosage forms has been developed. The absorption maxima were found at 220nm for ramipril and 297nm for telmisartan using 0.1N NaOH as solvent. Beer’s law was obeyed for both the d...

Rambabu R, Vidyadhara S and Subbarao J*

UTILITY OF HADKAR FACTOR IN THE DETERMINATION OF CRITICAL MICELLE CONCENTRATION OF SURFACTANTS

PAGE 36-39

The drop weight method was used to determine the interfacial tension between organic liquid and solutions of different concentrations of the surfactant, sodium lauryl sulphate (SLS), using Hadkar factor. Two experiments were performed to determine the interfacial tension. In the first experiment ...

Hadkar B. U.* and Sanghavi N. B.

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