The final efficacy and safety of N-mannich base prodrugs of amides of ibuprofen, IBMB-M and IBMB-P, were confirmed by performing pharmacological studies on animals. The antiinflammatory activity of the prodrugs was evaluated by rat paw edema method. The results confirmed that both the prodrugs ha...

The present study was undertaken to evaluate anthelmintic activity of ethanolic and aqueous bark extracts of Ficus glomerata against Eudrilus eugeniae. For this study, we used various concentrations (25-100 mg/mL) of aqueous and ethanolic extracts and these were evaluated in the bioassay involvin...

A simple, accurate, precise high-performance liquid chromatographic (HPLC) method has been developed and validated for the simultaneous determination of abacavir sulphate (ABA) and lamivudine (LAM) in combined dosage form. Separation was performed on a C18 column [Agilent ODS UG 5 column, 250 mm ...

A simple, rapid, accurate, precise and reproducible UV spectroscopic method has been developed for the simultaneous estimation of pitavastatin calcium and fenofibrate in bulk and pharmaceutical dosage form. The method is based on simultaneous equation method. Pitavastatin calcium and fenofibrate ...

A precise, simple, responsive and feasible ultra-fast liquid chromatography (UFLC) method for novel analysis of quercetin in aqueous and alcoholic extracts of Camellia sinensis with internal standard has been developed. The analysis was carried out on a Phenomenax-C18 column (250 × 4.6mm, 5μm)....

The aim of the min present study was to develop pantoprazole suspension containing delayed release (DR) microspheres to target the drug release intestine. This study is divided into two sections, first one is to prepare DR pantoprazole microspheres and second is to formulate into reconstitutional...

The present study describes the isolation and extraction of collagen and collagen peptide from the crude, fish offals of the common Indian macreal fish (Rastrelliger kanagurta), which makes the total extraction process more economical compared to the existing industrial procedures. Hydrolyzed col...

Ratio derivative spectrophotometric method has been developed for the simultaneous determination of artemisinin and curcumin. The overlapping spectra of both drugs were resolved by making use of the first-derivative of the ratios of their direct absorption spectra. The derivative ratio absorbance...