Oxidative stress is believed to be a key factor in the pathogenesis and perpetuation of the mucosal damage in inflammatory bowel disease. The investigation was envisaged to assess the protective effect of diethyl ether extract of leaves of Aegle marmelos Corr. (DEAM) in view of reported anti-infl...
Oxiconazole nitrate is antifungal drug having low solubility. An attempt was made to increase the solubility by solid dispersion technique. Twelve solid dispersion formulations were prepared by solvent evaporation and kneading method using β-cyclodextrin and 2-hydroxypropyl β-cyclodextrin as ca...
A simple, accurate and rapid high performance thin layer chromatography (HPTLC) -densitometry method was developed for separation and determination of cefixime (CEF) as an oral third generation cephalosporin antibiotic and ofloxacin (OFL) as a fluoroquinolone derivative used as antibacterial in p...
Chondroitinases are useful in treating cancer and spinal cord injuries. The work reported so far does not focus on production of fungal chondroitinase. The present study focuses on the optimization of cultural conditions using design of experiments for production of chondroitinase by a fungal iso...
The main aim of the study was to carry out anti-inflammatory activity of Thevetia peruviana in acute and sub acute in vitro models. The hydro-alcoholic extract showed the presence of carbohydrate, tannins, flavonoids, terpenes, steroids, glycosides and alkaloids. Against protein denaturation, the...
Development and modification of Ayurvedic classical formulations into widely acceptable dosage forms is an important area to be focused in the present era. The designing of liquid dosage form has generally been emphasized on the basis of ease of administration to those individuals who have diffic...
The present investigation is an attempt to show that solids can also be wisely used to act as solvent precluding the use of organic solvents. Present study describes the application of solvent character of eutectic liquid consisting of phenol and niacinamide in 25:10 ratio (PNM 2510) on weight ba...