Table of Contents

April  2015

  • Volume 52
  • Issue 04
  • Page Nos. 52

Original Research Articles

CURCUMIN, OCIMUM SANCTUM AND GINKGO BILOBA IMPROVE HEMODYNAMIC, BIOCHEMICAL AND HISTOARCHITECTURAL ALTERATIONS IN ISOPROTERENOL INDUCED CARDIAC DAMAGE

PAGE 5-14

Curcumin, Ginkgo biloba and Ocimum scantum are traditionally used for the treatment of cardiovascular and hepatic disorders. The effects of curcumin, Ginkgo biloba and Ocimum sanctum were studied [acute (4 days) and chronic (60 days)] alone and in combination (60 days) on isoproterenol (ISO) indu...

Suresh R Naik*, Vishnu N Thakare and Vandana S. Panda

NOVEL ZERO ORDER UV-SPECTROPHOTOMETRIC AND FIRST ORDER DERIVATIVE UV-AUC METHODS FOR ESTIMATION OF ETOMIDATE IMPARTING HYDROTROPIC SOLUBLIZATION

PAGE 15-20

Simple, novel UV-spectrophotometric methods have been developed and validated for the estimation of etomidate imparting a hydrotropic solublization phenomenon. Etomidate is an imidazole derivative, approved as a short acting intravenous anesthetic having poor water solubility. As the UV-spectroph...

Atul A. Shirkhedkar and Saurabh B. Ganorkar*

FORMULATION AND EVALUATION OF EFAVIRENZ COMPACTS BY LIQUISOLID TECHNIQUE FOR SOLUBILITY ENHANCEMENT

PAGE 21-27

The aim of this study was to improve the bioavailability by enhancing the solubility of efavirenz, a poor water soluble, anti-viral drug by using liquisolid technique. Different liquisolid formulations were prepared by using various non-volatile hydrophilic solvents. Microcystalline cellulose (Av...

Ramya V, Abbas Z and Swamy NGN*

FORMULATION DEVELOPMENT OF MATRIX TABLET OF STAVUDINE BY USING CARBOXY METHYL TAMARIND KERNEL POWDER AS A NOVEL DRUG RELEASE RETARDING AGENT

PAGE 28-36

The aim of the present study was to evaluate carboxy methyl tamarind kernal powder as a novel drug release retarding agent. To evaluate the same, sustained release matrix tablets of stavudine were prepared by using HPMC K4M and carboxy methyl tamarind kernal powder, by using a direct compression ...

Karmarkar R. R, Wagh M. P, Baviskar S.R*, Patil S.H and Khawshe S. K

IN VITRO ANTIMICROBIAL ACTIVITY OF CYNODON DACTYLON (L.) PERS. LEAF EXTRACTS. ANTIMICROBIAL ACTIVITY BY ZONE OF INHIBITION ESTIMATION

PAGE 37-41

The present study was undertaken to evaluate in vitro antimicrobial activity of the successive leaf extracts of Cynodon dactylon in petroleum ether, ethyl acetate, acetone, ethanol, methanol and water, against various gram positive & gram negative bacterial strains using zone of inhibition. B...

Pawaskar S. M.* and Sasangan K. C.

Short Notes

DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR RILPIVIRINE HYDROCHLORIDE IN BULK AND use in analysis of PREPARED NANOSUSPENSION

PAGE 42-46

A simple, precise, accurate and robust RP-HPLC-PDA method was developed and validated for the determination of rilpivirine hydrochloride in tablet dosage forms. Reverse-phase chromatography was performed on a BDS hypersil (250 mm × 4.6 mm, 6 μm) column of Waters HPLC with Empower software and w...

Manchala Madhuri, Kanagala Vijaya Sri* and Ganapath Vinay Jain

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