Table of Contents

March  2018

  • Volume 55
  • Issue 03
  • Page Nos. 90

ISSN: 0019-462X (print)

Guest Editorial

Editorial INDIAN DRUGS MARCH 2018

PAGE 5-6

Dear Reader,

On the 22nd of February this year, INDIAN DRUGS celebrated its 55th Annual Day at the IIT Bombay campus in Powai. 55 years of publishing a Scientific Journal regularly every month is truly an accomplishment of which I am grateful to be able to contribute to. I sincerely appre...

Dr. George Patani, Ph.D.

Original Research Articles

SYNTHESIS, ANTIBACTERIAL EVALUATION AND DOCKING STUDIES OF SOME NOVEL ISATIN DERIVATIVES

PAGE 7-12

Benzylimino isatin Mannich bases (IS1 & IM1-IM6) were designed manually and synthesized by the simple Mannich reaction. The synthesized compounds were confirmed by means of their spectral evidence (FTIR, 1H NMR and ESI-MS). The antibacterial activities were carried out with Gram +ve as well a...

Venkateshan. N.a*, Rajapandi. R.b and Kaniga. P.a

MICROWAVE ASSISTED SYNTHESIS OF BIPHENYL BASED SCHIFF’S BASES AND THEIR ANTIMICROBIAL EVALUATION

PAGE 13-18

Schiff’s base constitutes a significant class of compounds for new drug development. They are widely used for industrial purposes and also exhibit a broad range of biological activities. The search for Schiff’s base containing compounds with more selective activity and lower side effects cont...

Somani R.a*, Dubey P.a and Zine S.a

QbD Assisted RP-HPLC Method for Identification of Terazosin in Bulk Drug and Pharmaceutical Sample

PAGE 19-26

Reversed Phase High Performance Liquid Chromatographic (RP-HPLC) proves to be a convenient and reliable technique for the identification of various compounds, such as pharmaceutical drugs of chemical as well as phyto origin, food compounds and others. Analytical method for the estimation of alpha...

Dhal C.a*, Rajput D.b, Tiwari V.b, Teotia A.b, Singh G. N.b

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR FLUTICASONE FUROATE AND VILANTEROL IN PHARMACEUTICAL FORMULATIONS

PAGE 27-31

A simple, rapid, accurate and stability indicating High Performance Liquid Chromatographic method was developed and validated for the simultaneous determination of vilanterol (VTL) and fluticasone furoate (FFE) in pure and in pharmaceutical formulations using C18 Column and methanol: acetonitrile...

Masimukku S. K.a Chintala R.b*

RP-HPLC and HPTLC Stability Indicating Assay Methods for Ivermectin in Bulk and Tablet Dosage Form

PAGE 32-42

Simple, rapid, precise, accurate RP-HPLC and HPTLC methods have been developed and validated for ivermectin in bulk and its marketed formulation. RP-HPLC method for drug was achieved on Grace C18 (250 mm X 4.6 ID, Particle size; 5 μ) column using mobile phase acetonitrile: 10 mM phosphate buffer...

Wani G. P.a and Jadhav S. B.b*

NEUROPROTECTIVE EFFICACY OF SWARNA BHASMA ON SLEEP DEPRIVED INDUCED COGNITIVE IMPAIRMENT IN RATS

PAGE 43-48

The present investigation was carried out to evaluate neuroprotective efficacy of swarna bhasma on cognitive impairment induced by sleep deprivation in rats. Radial arm maze and elevated plus maze methods were used for behavioural testing in rats. The male albino rats were divided into five exper...

Khan A.Y.a*, Sheikh A. A.b, Tenpe C. R.a, Patole A. M.a and Biyani K. R.b

A PROSPECTIVE STUDY BASED ON THE EVALUATION OF DAILY AND INTERMITTENT DOSAGE REGIMEN OF ANTI-TUBERCULAR (ATT) DRUG THERAPY

PAGE 49-57

Anti-TB drug induced hepatotoxicity causes treatment interruption, poor compliance, increased mortality and morbidity, and modification of treatment regimen. Hence, we need to assess the effect of dosing schedule of daily and intermittent regimens and identify patients with increased risk of deve...

Sankar V.a*, Nimitha M.a and Rama P.a

Short Notes

SIMULTANEOUS ESTIMATION OF ATAZANAVIR SULFATE AND RITONAVIR IN MARKETED FORMULATIONS – UV SPECTROSCOPIC THREE WAVELENGTH METHOD

PAGE 58-61

Three-wavelength spectrophotometric method has been developed for the simultaneous estimation of atazanavir sulfate (ATZ) and ritonavir (RIT) in pharmaceutical preparations. The absorbance value at 279.7nm was used for the estimation of ATZ where RIT showed zero absorbance. The absorbance value f...

Kasula P.a and K. V. Nanda Kumara*

STUDY OF PEANUT HUSK POWDER AS SUPERDISINTEGRANT IN THE FORMULATION OF FAST DISSOLVING TABLETS OF ONDANSETRON HYDROCHLORIDE

PAGE 62-64

Fast dissolving tablets are considered as one of the rapidly moving products of novel drug delivery systems in the present pharmaceutical market. The development of new excipients for this technology is challenging task for pharmaceutical technologists. Disintegrants are one of the most important...

Chandra Sekhara Rao G.a*, Aathira O. S.a and Jyothsna T.a

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