Dear Reader,

On the 22nd of February this year, INDIAN DRUGS celebrated its 55th Annual Day at the IIT Bombay campus in Powai. 55 years of publishing a Scientific Journal regularly every month is truly an accomplishment of which I am grateful to be able to contribute to. I sincerely appre...

Benzylimino isatin Mannich bases (IS1 & IM1-IM6) were designed manually and synthesized by the simple Mannich reaction. The synthesized compounds were confirmed by means of their spectral evidence (FTIR, 1H NMR and ESI-MS). The antibacterial activities were carried out with Gram +ve as well a...

Schiff’s base constitutes a significant class of compounds for new drug development. They are widely used for industrial purposes and also exhibit a broad range of biological activities. The search for Schiff’s base containing compounds with more selective activity and lower side effects cont...

Reversed Phase High Performance Liquid Chromatographic (RP-HPLC) proves to be a convenient and reliable technique for the identification of various compounds, such as pharmaceutical drugs of chemical as well as phyto origin, food compounds and others. Analytical method for the estimation of alpha...

A simple, rapid, accurate and stability indicating High Performance Liquid Chromatographic method was developed and validated for the simultaneous determination of vilanterol (VTL) and fluticasone furoate (FFE) in pure and in pharmaceutical formulations using C18 Column and methanol: acetonitrile...

Simple, rapid, precise, accurate RP-HPLC and HPTLC methods have been developed and validated for ivermectin in bulk and its marketed formulation. RP-HPLC method for drug was achieved on Grace C18 (250 mm X 4.6 ID, Particle size; 5 μ) column using mobile phase acetonitrile: 10 mM phosphate buffer...

The present investigation was carried out to evaluate neuroprotective efficacy of swarna bhasma on cognitive impairment induced by sleep deprivation in rats. Radial arm maze and elevated plus maze methods were used for behavioural testing in rats. The male albino rats were divided into five exper...

Anti-TB drug induced hepatotoxicity causes treatment interruption, poor compliance, increased mortality and morbidity, and modification of treatment regimen. Hence, we need to assess the effect of dosing schedule of daily and intermittent regimens and identify patients with increased risk of deve...

Three-wavelength spectrophotometric method has been developed for the simultaneous estimation of atazanavir sulfate (ATZ) and ritonavir (RIT) in pharmaceutical preparations. The absorbance value at 279.7nm was used for the estimation of ATZ where RIT showed zero absorbance. The absorbance value f...

Fast dissolving tablets are considered as one of the rapidly moving products of novel drug delivery systems in the present pharmaceutical market. The development of new excipients for this technology is challenging task for pharmaceutical technologists. Disintegrants are one of the most important...