Tadalafil (TAD) is a selective phosphodiesterase type 5 inhibitor. It is utilized for the treatment of erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It enhances the sexual performance in males during copulation. It is recommended in the guidelines as first-line therapy, bec...

The ancient literature of traditional Indian medicine indicate the potential medicinal values of Gmelina arborea as an important source of chemicals of enormous medicinal and pharmaceutical importance such as flavonoids, alkaloids, arboreol, isoarboreol, methyl arboreol, gummadiol, gmelanone, gme...

The aim of present work was to develop a gastroretentive floating raft forming film of atenolol using solvent casting technique. The films were characterized in terms of drug-excipient compatibility by FTIR, drug content, swelling, folding endurance, thermal behaviour by DSC, effect of processing...

Sensitive liquid chromatographic methods for the determination of two genotoxic impurities, namely hydrazine hydrate and 4-bromomethyl benzonitrile, in letrozole have been presented. Method-A is the pre-column derivative UFLC method for the determination of hydrazine hydrate with 4-methoxy benzal...

Two new, simple, accurate and sensitive UV spectrophotometric methods have been developed and subsequently validated for the simultaneous estimation of zidovudine and lamivudine in a fixed dose combination. Zidovudine and lamivudine have an absorption maxima at 267.3 nm and 272.3 nm respectively....

Bauhinia racemosa Lam. is an important plant in Ayurvedic medicine. The flower buds and their Ayurvedic preparations are well known for anti-inflammatory and anti-ulcer activity. However, still no analytical method has been developed for the identification and quantification of its phytoconstitue...