Microfabrication is a collection of techniques developed to fabricate micron sized features, best suited to develop the novel drug delivery microdevices. microfabrication techniques were originally developed in the microelectronics industry to produce functional devices on the micron scale such a...
The aerial roots of Ficus benghalensis Linn (Moraceae) have been reported to have immunomodulatory, anti-bacterial and hair growth promoting activities. There are no reports on pharmacognostical and phytochemical investigations of these aerial roots. The aim of the present study was evaluation of...
The main objective of the present study was to enhance the solubility and dissolution rate of poorly water soluble aceclofenac using its solid dispersion with β-cyclodextrin. FTIR and DSC study was carried out to find out any incompatibility. The phase solubility of drug was carried out in 1, 2,...
A novel ultra-fast liquid chromatography (RP- UFLC) analytical method has been developed to quantify opipramol in tablet formulations. The determination was carried out by means of a Phenomenex Luna C8 Column (250×4.60mm, 5μ); potassium dihydrogen phosphate buffer of pH 2.4 and acetonitrile was...
A simple, accurate and precise UV spectrophotometric method has been developed for the simultaneous estimation of brimonidine tartrate (BRT) and brinzolamide (BRZ) using methanol as solvent. The λmax for BRT and BRZ were found to be 244 nm and 253 nm, respectively. The linearity was found in the...
A simple, precise and accurate isocratic RP-HPLC method was successfully developed for the simultaneous determination of chlorpheniramine maleate (CPM), phenylephrine hydrochloride (PHE) and ibuprofen (IBU) in bulk and pharmaceutical preparation. The separation of the drugs was achieved using Ine...
An accurate, sensitive, precise, economic and rapid isocratic Reverse Phase High Performance Liquid Chromatography method was developed complying Quality by Design (QbD) trends and validated for determining doxycycline hyclate in bulk drug, tablet and capsule dosage form. The method was optimized...
NCV I and AC II are the two herbal immunomodulatory preparations being used in our centre for the treatment of acquired immunodeficiency syndrome (AIDS) for the past 20 years. The objective of this study is to check whether these drugs possess any antiviral activity in vitro and in vivo. In vitro...