Articles Accepted

Silver nanoparticles (AgNPs) synthesized using green methods, particularly utilizing plant extracts, have emerged as promising candidates for anticancer therapy. This paper presents the formulation and comprehensive evaluation of green synthesized plant-based silver nanoparticles for their therapeutic potential in cancer treatment. The green synthesis approach offers advantages such as eco-friendliness, cost-effectiveness, and scalability, making it an attractive option for nanoparticle synthesis. Plant extracts serve as both reducing and stabilizing agents during the synthesis process, resulting in the formation of biocompatible nanoparticles with enhanced anticancer properties. The formulation process involves optimizing synthesis parameters such as extract concentration, reaction time, and temperature to achieve nanoparticles with desirable characteristics. Evaluation of the synthesized nanoparticles includes physicochemical characterization using transmission electron microscopy (TEM) and Fourier-transform infrared spectroscopy (FTIR). Furthermore, the therapeutic potential of green synthesized plant-based AgNPs against cancer is assessed through in vitro and cytotoxicity assays. The findings demonstrate the efficacy of these nanoparticles in inhibiting cancer cell proliferation, inducing apoptosis, and suppressing tumor growth. Overall, the formulation and evaluation of green synthesized plant-based silver nanoparticles offer promising insights into their therapeutic prospective for anticancer applications, highlighting their potential as novel and sustainable nanotherapeutics in the fight against cancer.