Articles Accepted

Assessment of adherence to medications and prevalence of depression among hemodialysis patients
by Dr. hany, 05 Aug 2023

Background: End-stage kidney disease requires renal replacement therapy due to the gradual decline in the kidneys' ability to function. Hemodialysis is the most commonly used renal replacement therapy worldwide, and it frequently leads to neuropsychiatric issues, with depression being the most prominent. Non-adherence to drug therapy is considered one of the most significant drug-related issues among hemodialysis patients, and various studies have shown that non-adherence is common. The study aimed to determine the prevalence of depression and non-adherence to drug therapy and to identify predictors of depression and non-adherence among hemodialysis patients. Subjects and Methods: The cross-sectional study included 99 patients and 33 apparently healthy control subjects. The data collected encompassed personal and disease-related variables The data collected included personal and disease-related variables from AL-Yarmouk Hospital during the period from 20th July to 20 August 2019. Adherence to medication was assessed using a validated medication adherence scale, and participants' depression levels were evaluated utilizing a standardized depression questionnaire. Results: The median age of the patients was 51.2 ± 14.4 years, with the majority being male (67.7%). Depression was prevalent in 86.9% of patients, significantly higher than the control group's prevalence of 63.6%. The median depression score was significantly higher among patients than in the control group. No significant differences were observed in sociodemographic and disease parameters between patients with or without depression. Non-adherence was common, with 47.47% of patients being non-adherent. The mean age and college education were significantly higher in adherent patients than in non-adherent patients. Conclusions: Depression is a prevalent issue among hemodialysis patients, and it is not related to any personal or medical features. The study also revealed a high rate of non-adherence to drug therapy among hemodialysis patients.

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