Table of Contents

July  2022

  • Volume 59
  • Issue 7
  • Page Nos. 80

Editorial

INERTIA TO ADOPT DIGITAL TECHNOLOGIES IN PHARMA

PAGE 5-6

Dear Reader,

During the turn of the century and early millennium, when the potential of online pharmacies was predicted, there was widespread hue and cry including the regulators.The regulator agencies had cautioned against any proposal for online selling of medicines and had declared suc...

Dr. Gopkakumar G. Nair

Editor

Indian Drugs

Review Article

LIPID AS AN EXCIPIENT FOR DESIGN AND DEVELOPMENT OF FORMULATIONS

PAGE 7-20

Lipids are present abundantly in human body in several forms. Different types of lipids are available with diverse physical properties, based on which suitable lipids can be selected for development of formulations. Lipids are also available for specific purposes like lubrication, emulsification,...

Apoorva V. Morea *, Bharat V. Dhokchawleb, Savita J. Taurob and Savita V. Kulkarnic

Original Research Articles

SYNTHESIS, SPECTRAL DERIVATIZATION WITH ANTICANCER AND ANTIMICROBIAL POTENTIAL EVALUATION OF NOVEL NAPHTHOIC ACID SUBSTITUTED IMIDAZO [2,1-B][1,3,4]THIADIAZOLES

PAGE 21-27

A total of 12 substituted naphthoic acid-linked imidazothiadiazole derivatives were synthesized and evaluated for their anticancer potential against human lung cancer cell line A-549 and also for their antimicrobial activity by measuring zone of inhibition (mm) against S. aureus, B. subtilis and ...

Satvir Singha , Divya Bhandaria *, Monika Guptab and Gursewak Singhb

EVALUATION OF DIACEREIN MICROSPHERE MANUFACTURED BY FLUID BED BOTTOM SPRAY COATING TECHNIQUE AS SUSTAINED RELEASE DRUG DELIVERY FORM

PAGE 28-36

Diacerein (DCN), an anti- inflammatory, anti-osteoarthritic drug having short-acting properties was formulated as microsphere following fluid bed bottom spray coating technique for sustained release drug delivery, where HPMC (6cps) and ethyl cellulose (N7) were used as coating polymers. Assay of ...

Soumen Mukhopadhyaya *, Nilendra Chatterjeea and Tapan K. Chatterjeeb

COMPARATIVE QUANTITATIVE ESTIMATION OF COLCHICINE IN CORMS OF DIFFERENT COLCHICINE BEARING PLANTS USING HPLC AND HPTLC METHOD

PAGE 37-43

Colchicine is an alkaloid which has been reported to possess anti-gout, anti-rheumatic, antiparasitic and anticancer potential. It is a toxic natural product obtained from plants of the genus Colchicum (C. autumnale and C. luteum), Gloriosa superba, and Iphigenia indica. In the present study, thr...

Sameer Sapraa , Yashika Bhallab, Bhawna Choprac and Ashwani K. Dhingrac *

NOVEL SPECTROPHOTOMETRIC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF ABACAVIR SULPHATE, LAMIVUDINE AND DOLUTEGRAVIR SODIUM IN DOSAGE FORM

PAGE 44-51

Double Divisor ratio spectra derivative method was developed and validated for a ternary mixture containing abacavir sulphate (ABA), lamivudine (LAM) and dolutegravir sodium (DOL) in distilled water. The method is based on dividing the absorption spectra of ternary mixture by the sum of absorptio...

Sapna M. Rathoda * and Paresh U. Patelb

SIMPLE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS QUANTIFICATION OF SAXAGLIPTIN AND DAPAGLIFLOZIN IN RAT PLASMA

PAGE 52-59

A simple HPLC method was developed for the simultaneous estimation of saxagliptin and dapagliflozin in rat plasma. The separation has been achieved by C8 Eclipse plus column (25cm x 5cm x 4.6µ) at 1 mL min-1 flow rate. The mobile phase comprises of 0.01 % trimethylamine in ...

Aksa Kuriana , Rekha T. N.a , Bhagyalakshmi C.a , Syed S. Ahmedb, Yunus T. Pashac , Ramesh B. c and Manish Majumdera *

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF EXEMESTANE IN NANOEMULSION BY RP HPLC

PAGE 60-64

A simple, precise, reproducible and sensitive RP HPLC method was developed and validated for the quantification of exemestane (EXM) in nanoemulsion. The method was developed using Phenomenex C18 column (250 mm × 4.6 mm i.d., 5 µm) and acetonitrile: methanol (40:60 V/V) was used as mo...

Bhupendra G. Prajapatia *, Bhavesh B. Prajapatia and Sapna M. Rathodb

ENHANCED ANTICANCER POTENTIAL OF IMIPRAMINE IN CONJUGATION WITH NIACIN IN DENA INDUCED HEPATOCELLULAR CARCINOMA

PAGE 65-71

Hepatocellular carcinoma (HCC) is constantly seeking the interest of researchers as an untreatable and fatal disease, attaining second position so far worldwide. Our study provides us an opportunity to explore new potential therapeutic combinations in this regard. We hypothesized that the antican...

Alisha Rawata , Meenakshi Sajwana , Yamini Chandolaa , Himani Nautiyalb and Nidhi Nainwalc *

Short Communications

POSSIBLE DESTRUCTION OF SARS-COV-2 BY SODIUM DEOXYCHOLATE

PAGE 72-73

The objective of this study was to focus on the antiviral activity of a bile salt, namely sodium deoxycholate. There is a possibility of killing severe acute respiratory syndrome corona virus-2 due to the destruction of its protein and lipid overcoat by sodium deoxycholate alone or with drugs tho...

Durga Pandeya *, Deepti Jaina , Girijesh Pandeyb and Surendra Jainc

DESIGN, DEVELOPMENT AND EVALUATION OF ALOGLIPTIN AND METFORMIN HYDROCHLORIDE BILAYER TABLET

PAGE 74-76

The objective of the present work was to formulate and evaluate bilayer tablets of alogliptin and metformin HCl. Combining alogliptin with metformin HCL gives additional benefits in comparison with either drug alone and could be considered for patients whose quality of life is impaired by diabete...

Deepak S. Jata *, Swati G. Talelea , Akshada A. Bakliwala and Anil G. Jadhava

Current Issue
August 2022
Quick Contact