Current Issue

June  2025

  • Volume 62
  • Issue 6
  • Page Nos. 68

Editorial

PESTICIDES AND PHARMACEUTICALS – AN INTRICATE RELATIONSHIP

PAGE 5-6

Dear Reader,

Academicians, economists and industrialists tend to segregate various segments of industry - where chemistry and chemical technology play a major role - and often deal with them rather independently of each other – be it pharmaceuticals, perfumes and fragrances, ...

Dr. Nagaraj Rao

Associate Editor

Indian Drugs

Review Article

ADVANCES IN TREATING DEPRESSION

PAGE 9-21

It is normal to feel temporarily depressed when facing situations such as the loss of someone close, or experiencing serious financial or domestic issues; however, when these depressed feelings intensify and last much longer, it could be due to clinical depression. Around the world, millions of ...

Lohit V. Tutupallia*

Original Research Articles

MOLECULAR DOCKING STUDIES WITH PHYTOCONSTITUENTS OF TINOSPORA SINENSIS TARGETING SARS-COV-2 PROTEIN USING AUTODOCK VINA

PAGE 22-27

Drug discovery is time-consuming and resource-intensive, but computational approaches offer a more efficient alternative. The urgency for antiviral treatments became evident during the SARS-CoV-2 pandemic due to the virus’s rapid spread and mutations. This study utilizes computational drug ...

Christy Sajia *, Rajeswary K. Balachandrana , Aneeza M. Nizara , Sruthi Shaijua , Navya Sajua , Bobby S. Prasadb and Prasanth Francisc

ETODOLAC LOADED MESOPOROUS SILICA NANOPARTICLES BASED TOPICAL GEL FOR TREATMENT OF INFLAMMATION

PAGE 28-36

This study explores a topical hydrogel incorporating mesoporous silica nanoparticles (MSNs) loaded with etodolac (ETD) for inflammation treatment. MSNs were synthesized via the sol-gel method and loaded with ETD using adsorption. The ETD-MSNs were formulated into a gel using Carbopol® Ultrez. ...

Jayesh R. Guptaa,c, Shivali A. Nigadea , Sankalp A. Gharata and Munira M. Momina,b*

DEVELOPMENT AND OPTIMIZATION OF A QUALITY BY DESIGN-DRIVEN HPLC METHOD FOR CURCUMIN QUANTIFICATION

PAGE 37-44

The research study involves development and validation of a robust RP-HPLC technique for curcumin quantification using Analytical Quality by Design (AQbD). Key method parameters such as composition of mobile phase, temperature of column, and flow rate were optimized using a 33 -level factorial ...

Saurabh Morpariaa , Chaitanya Methaa , Shrutee Pawara and Vasanti Suvarnaa *

RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF REMDESIVIR IN IV FORMULATION

PAGE 45-49

The overall effect of the SARS-CoV-2 virus, instigating COVID-19, has highlighted the urgent need for effective treatments. Remdesivir, the only FDA-approved antiviral for severe COVID-19 in adults and children, requires precise analytical methods for its pharmaceutical formulation. Current HPLC ...

Mukesh P. Ratnaparkhia *, Avinash R. Tekadea , Shailendra S. Salvankara , Sampada D. Dalvib, Gajanan M. Kulkarnia and Mayur G. Markanda

COMPARATIVE ASSESSMENT OF THE BIOACTIVE POTENTIAL OF PIMENTA DIOICA STEM EXTRACTS: ANTIOXIDANT AND ANTI-PROLIFERATIVE PROPERTIES

PAGE 50-56

This research explores the antioxidative effects and anti-proliferative action of Pimenta dioica stem extracts. The ethanolic and aqueous extracts were evaluated for their ability to neutralize DPPH radicals, reduce ferric ions, scavenge hydrogen peroxide and exhibit cytotoxic effects on cancer ...

Irfana M. K.a and Jayasheela Da *

Short Communications

DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF RISPERIDONE AND QUERCETIN IN SLNS FORMULATION

PAGE 57-59

A UV spectroscopic method was developed to measure risperidone (Ris) and quercetin (Que) using methanol as a solvent. The method was validated for precision (intraday and interday), limit of quantification (LOQ), limit of detection (LOD and accuracy, proving to be sensitive, fast, accurate, and ...

Shilpa P. Chaudharia and Neha G. Kurea *

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