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Academicians, economists and industrialists tend to segregate various segments of industry - where chemistry and chemical technology play a major role - and often deal with them rather independently of each other – be it pharmaceuticals, perfumes and fragrances, ...
It is normal to feel temporarily depressed when facing situations such as the loss of someone close, or experiencing serious financial or domestic issues; however, when these depressed feelings intensify and last much longer, it could be due to clinical depression. Around the world, millions of ...
Drug discovery is time-consuming and resource-intensive, but computational approaches offer a more efficient alternative. The urgency for antiviral treatments became evident during the SARS-CoV-2 pandemic due to the virus’s rapid spread and mutations. This study utilizes computational drug ...
This study explores a topical hydrogel incorporating mesoporous silica nanoparticles (MSNs) loaded with etodolac (ETD) for inflammation treatment. MSNs were synthesized via the sol-gel method and loaded with ETD using adsorption. The ETD-MSNs were formulated into a gel using Carbopol® Ultrez. ...
The research study involves development and validation of a robust RP-HPLC technique for curcumin quantification using Analytical Quality by Design (AQbD). Key method parameters such as composition of mobile phase, temperature of column, and flow rate were optimized using a 33 -level factorial ...
The overall effect of the SARS-CoV-2 virus, instigating COVID-19, has highlighted the urgent need for effective treatments. Remdesivir, the only FDA-approved antiviral for severe COVID-19 in adults and children, requires precise analytical methods for its pharmaceutical formulation. Current HPLC ...
This research explores the antioxidative effects and anti-proliferative action of Pimenta dioica stem extracts. The ethanolic and aqueous extracts were evaluated for their ability to neutralize DPPH radicals, reduce ferric ions, scavenge hydrogen peroxide and exhibit cytotoxic effects on cancer ...
A UV spectroscopic method was developed to measure risperidone (Ris) and quercetin (Que) using methanol as a solvent. The method was validated for precision (intraday and interday), limit of quantification (LOQ), limit of detection (LOD and accuracy, proving to be sensitive, fast, accurate, and ...