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Pharmaceutical manufacturing has, for over a century, run on a simple concept: make one formulation, in one strength, at enormous scale. However, the medical fraternity knows how uneasily this sits alongside the reality of patients, who differ enormously in body weight, ...

Nitrosamine impurities, classified as human carcinogens, have been detected in pharmaceutical drugs over the past several years. They are distinguished by the presence of the nitroso functional group and may develop under numerous conditions, including manufacturing and shelf life. Metabolic ...

This study presents a novel nanotherapeutic strategy for the treatment of arthritis utilising copper nanoparticles prepared using leaf extract from Baliospermum solanifolium. Known for its antiinflammatory properties, the plant was used as a natural capping and reducing agent during the ...

Polycystic ovarian syndrome (PCOS) is an endocrine disorder affecting women during their fertile years, marked by hormonal imbalance, cystic ovaries and irregular menstruation. Pimenta dioica, a traditional medicinal plant, was evaluated for its therapeutic potential against PCOS using in silico ...

The emergence of SARS-CoV-2 virus as a major health hazard increased interest in traditional formulations from Ayurveda such as Ayush Kwath Churna (AKC), which are recognized for their ability to boost immunity. But due to the possibility of contamination, there is a need for an effective quality...

A reliable, innovative and stability-indicating HPTLC method was successfully developed and validated for estimating inosine pranobex (IP) in both bulk drug and pharmaceutical formulations using a Quality by Design (QbD) approach. To achieve systematic optimization, a Box-Behnken Design was ...

A simple, accurate, and precise reverse-phase high-performance liquid chromatography method was for developed simultaneously estimating paracetamol, guaifenesin, and phenylephrine hydrochloride in a combined dosage form. An Inertsil ODS-3V C18 column (250 mm × 4.6 mm, 5 µm) was used to separate...

Sutures play a critical role in wound closure and healing following surgical procedures, but can also act as a reservoir for microbial colonization, potentially leading to surgical site infections. To address this, the present study evaluated the antimicrobial efficacy of silk sutures coated with...

The research emphasizes the formulation development and evaluation of a polyherbal effervescent antidiabetic powder by incorporating Syzygium cumini (Jamun seeds), Pterocarpus marsupium (Vijaysar wood), and Withania coagulans (Paneer phool). These herbs were selected for their traditional ...