Dear Reader,

It is indeed heartening to note that Dr. D. Srinivasa Reddy, who has close research and professional connections with IDMA and other Pharma Associations and has received Awards also from Industry, has joined the Indian Institute of Chemical Technology (IICT), Hyderabad as the...

Alzheimer’s disease is a progressive neurodegenerative disease, usually associated with old age. With the increasing geriatric population throughout the world, it will pose a great socio-economic burden on the healthcare system and the caregivers. The clinically approved drugs for management of...

Quantitative Structure Activity Relationship (QSAR) model on a series of triazolinone derivatives acting as angiotensin II receptor using partial least squares regression analysis was performed to compute the relationship with 2D structure descriptors. The computational studies were performed wit...

The concept of mixed solvency is an emerging field which can serve as a new method for solubility enhancement and therefore deserves urgent attention of the scientific community to assess its efficiency and applicability. Mixed solvency concept suggests that each substance present on the earth wh...

The present study was proposed for assessing the variation in quality of some hepatoprotective polyherbal products that are widely available in the market. Different brands of marketed hepatoprotective formulations were evaluated in the present investigation with respect to qualitative analysis b...

A simple, sensitive, rapid, precise and accurate RP-HPLC method has been developed for simultaneous estimation of hydroquinone, allantoin and tretinoin from cream formulation. Chromatographic separation was achieved on a reversed-phase Inertsil C₁₈ (4.6 mm) I.D.× 250 mm, 5 µm) column...

A stability indicating reversed-phase high-performance liquid-chromatographic method for analysis of empagliflozin was developed and validated as per the ICH guidelines. Statistical design of experiment was applied for optimization, where independent variables used were methanol proportions in mo...

Azelnidipine is a dihydropyridine used as a calcium channel blocker. The main aim of this study was to develop a validated bio-analytical method (as per US-FDA and EMA guidelines) for in vivo pharmacokinetic and bioequivalence study of azelnidipine in human plasma by LC-MS/MS, API-4000. In this m...

The prime objective of the present study was to develop enteric coated chitosan capsule containing capecitabine for targeting colorectal cancer cells. The study describes a new colonic drug delivery system utilizing capsule shells prepared from chitosan. Coating of drug filled chitosan capsule wi...

A novel UV spectrophotometric method has been developed for the simultaneous estimation of ezetimibe and rosuvastatin in combined dosage form. Method is based on simultaneous equations method. The wavelengths selected for analysis were λ_max of ezetimibe: 231.2 nm and λ_max ...