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Let us get ready to face the global healthcare challenges with positive attributes and approaches to regulatory pathways.

Resisting evergreening and extreme imbalances in Intellectual Property and patient practices may be a good option to continue from the Uruguay Rou...

Lawsone, also known as hennotannic acid, is the natural pigment obtained from henna. Lawsone is chemically 2-hydroxy-1,4-naphthoquinone. The presence of the hydroxyl group is the major determinant of its biological activity. Lawsone is extracted from the henna plant by solvent extraction using no...

Quantitative structure activity relationship (QSAR) analysis of 1, 2-disubstituted benzimidazoles IMPDH inhibitors was studied for their antibacterial activity. The 2D QSAR model was developed using molecular suite (VLife MDS 4.3.1) on a set of 38 molecules. Multiple Linear Regression (MLR) was i...

Oral drug delivery is the most popular method of control and release of therapeutic agents for the management of diseases. The colon specific drug delivery systems are considered to attain targeted drug delivery to the large intestine specifically at colon. They provide local delivery for the tre...

Use of different seed priming treatments improves seed germination and thus increases plant growth and yield potential. Eco-friendly, cost-effective, simple, and effective seed treatments need to be developed for a high-consuming crop like chickpea (Cice rarietinum Lin.). In the present ...

Specific stability-indicating reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed and validated for the quantification of alimemazine in bulk drug and pharmaceutical dosage forms. Chromatographic separation was done on C 18 column (250 mm X 4.6 mm X 5 µm) us...

Commonly used organic solvents for spectrophotometric analysis of water insoluble drugs include alcohol, chloroform, benzene, methylene chloride, dimethyl formamide, acetonitrile, toluene, acetone and hexane. The main drawbacks of organic solvents are high value, toxicity and pollution. Hence, it...

Immunomodulators are substances that stimulate, restore, suppress, or help to produce (adjuvant) or increase the desired immune response. Portulaca quadrifida is a traditional plant in the Ayurvedic system of medicine which has been reported to show a variety of therapeutic activities. This study...

For determination of eliglustat tartrate, a new, specific, simple, accurate (recovery) and precise stabilityindicating HPLC method has been developed and validated according to ICH Q2(R1) guidelines. The HPLC method was developed using acetonitrile: 0.1 % orthophosphoric acid 40:60 (V/V) as mobil...

Oral conventional formulations like tablets, capsules and liquids have many limitations. Due to this and patient incompliance, there is a need to develop new formulations with better efficiency and stability. The aim of the present study was to develop and optimize fast dissolving Oro-dispersible...