Table of Contents

May  2024

  • Volume 61
  • Issue 5
  • Page Nos. 80

ISSN (Print) : 0019-462X

Guest Editorial

IS BEING FAIR … REALLY LOVELY?

PAGE 5-6

Dear Reader,

Fairness of skin is most sought after by the Asians and Africans and the whole world clamours for products which are for either (a) skin whitening; (b) skin lightening; or (c) skin bleaching.

The global ‘fairness’ products market is valued at USD 10 billion (` ~80...

Dr R K Sanghavi

Consultant - NeuroMarketing & TechnoRegulatory (Pharma & Nutra) and

Chairman – Nutraceutical Committee (IDMA)

Review Article

A REVIEW IN CURCUMINOIDS: CHEMISTRY, ANTICANCER ACTIVITY AND FUTURE PROSPECTS

PAGE 7-23

Curcumin is a biologically active phytochemical which manifests therapeutic activities in numerous health conditions, including cancer. Several curcuminoids obtained naturally and synthesized artificially also showcase anti-cancer and anti-tumorigenic effects. However, its water insolubility pose...

Pranjali Mishraa , Muskan Srivastava , Yashveer Gautama *, Monal Singha , Neeraj Vermab, Deepak S. Kapkotic , Shailendra P. Singhb, Anil K. Singhd and Devendra P. Raoe

Original Research Articles

IN SILICO MOLECULAR DOCKING STUDIES OF COUMARIN-CHALCONE HYBRIDS AGAINST SARS-COV-2 MAIN PROTEASE (6LU7)

PAGE 24-31

The present work aimed to explore efficient lead molecules to combat against COVID-19. Despite the extensive usage of repurposed medications for COVID-19 therapy due to their inadequacy to proper control of endangered pandemic, there is an urgent need to discover innovative compounds that are ver...

Sathish K. Konidalaa *, Vijay Kotrab, Ramu Saminenic , Abdul R. Shaikd, Lakshmi S. Nissankara Raoe , Risy N. Jamullamudif and Phani K. Kolag

OPTIMIZATION OF α-AMYLASE SYNTHESIS BY BACILLUS VELEZENSIS USING TAGUCHI EXPERIMENTAL DESIGN

PAGE 32-44

This research employs the Taguchi experimental design to optimize the production of α-amylase, a versatile enzyme with diverse industrial applications, using Bacillus velezensis. Thirteen key parameters, including pH, temperature, agitation, inoculum size, aeration and various carbon and nitroge...

Sasidhar Bhimanaa * and Saravanan Ravindranb

FORMULATION AND EVALUATION OF β-SITOSTEROL LOADED NIOSOMES FOR ENHANCED ANTIDIABETIC ACTIVITY: A POTENTIAL ALTERNATIVE IN TYPE 2 DIABETES MANAGEMENT

PAGE 45-51

Niosomes, vesicles formed by non-ionic surfactants, offer advantages in drug delivery by enhancing solubilization and encapsulating both lipophilic and hydrophilic drugs. This study focuses on β-sitosterol-loaded niosomes designed to protect its anti-diabetic properties. Formulated with Span™ ...

Priya Tiwaria * and Rajat Srivastavab

PREFORMULATION STUDIES AND PROSPECTIVE VALIDATION OF UV-SPECTROPHOTOMETRIC METHOD OF AMOXICILLIN TRIHYDRATE

PAGE 52-58

The current study was embarked upon to evaluate and assess the physicochemical characteristics of amoxicillin trihydrate. The determination and validation of UV-spectrophotometric for amoxicillin trihydrate was included in the study. The different physical characteristics used in preformulation, ...

Prarthna Lakheraa, Sonia Narwalb and Minkal Tutejab*

PREPARATION AND CHARACTERIZATION OF SOLID DISPERSION USEFUL IN MAKING SUBLINGUAL TABLETS OF PIROXICAM

PAGE 59-63

This study aimed to investigate the usage of solid dispersion (SD) to enhance the dissolution rate of the poorly soluble drug piroxicam for sublingual formulation. Poloxamer grade 407 (Kolliphor® P-407), a commercially available polymer, was chosen, and various solid dispersions with different w...

Manish Goyania , Meghraj Suryawanshibc* and Nikunjkumar Gandhia

Short Communications

DEVELOPMENT OF AN ACCURATE UV SPECTROSCOPIC METHOD FOR TINIDAZOLE IN VAGINAL BUFFERS

PAGE 64-67

A precise UV spectroscopic method was developed for accurately quantifying tinidazole (TNZ) using the Shimadzu 1900i UV spectrophotometer. Different sample solutions containing TNZ were scanned across a range of concentration 6 µg mL-1 to 26 µg mL-1 between 200-400 nm, generating overlay TNZ sp...

Sakshi M. Shaha , Ilyas H. Momina , Riya M. Patela and Shreeraj H. Shaha *

IN VITRO-IN VIVO CORRELATION (IVIVC): TAMOXIFEN NANOSPHERES

PAGE 68-69

The primary goal of this study was to establish an in vitro-in vivo correlation (IVIVC) for tamoxifen (TAM)- loaded polycaprolactone-chitosan nanospheres. The plasma attention of TAM and time records have been used to calculate the pharmacokinetic parameters. Cmax for the nano spheres stayed dete...

Phalguna Yadagiria * and Michael Wombeogoa

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