Table of Contents

January  2022

  • Volume 59
  • Issue 1
  • Page Nos. 74

Editorial

NEED FOR PARTICIPATION BY RESEARCHERS ON RELATED REGULATORY POLICY MAKING AND ADVOCACY

PAGE 5-6

Dear Reader,

Many bills and proposals are being mooted and moved by the present Government in response to public representations and also to resolve internal constraints and for operational reasons. Regulatory aspects are closely linked to research and innovation. However, the Indian rese...

Dr. Gopakumar G. Nair

Editor

Indian Drugs

Review Article

AN INSIGHT INTO PRIVILEGED SCAFFOLDS IN TUBERCULOSIS: DEVELOPMENTAL ASPECTS AND IMPLICATIONS IN DRUG DESIGN

PAGE 7-22

Tuberculosis remains a major threat to mankind, becoming more deadly due to COVID-19 pandemic. The worldwide scenario is daunted by additional factors such as drug resistance, non-adherence and complexity of the treatment. To overcome these obstacles, there is a constant need for novel drug devel...

Rani. A. Shindea , Vasanti. M. Suvarnaa and Arundhati. N. Abhyankara *

Original Research Articles

SYNTHESIS, SPECTRAL STUDIES AND BIOLOGICAL ACTIVITY OF SOME IMIDAZO [2, 1-B] [1, 3, 4] THIADIAZOLE DERIVATIVES

PAGE 23-27

Benzoic acid substituted imidazo[2,1-b][1,3,4]thiadiazoles were synthesized using appropriate reaction scheme. The synthesized derivatives were then purified and elucidated for their structure by measuring their melting points, infra-red spectra and proton NMR spectra. The progress of the reactio...

Satvir Singha *, Divya Bhandaria , Monika Guptab, Chamanpreet Kaurb, Anju Ranib and Sunita Devib

INFLUENCE OF INTERACTION OF MILK FAT ON RELEASE, CHARACTERISTICS AND ABSORPTION OF THEOPHYLLINE

PAGE 28-33

Considerable evidence that drug bioavailability is influenced by food, in conjunction with the poor and erratic bioavailability of sparingly soluble drugs, serve as a stimulus in the research field for examining new formulations that may provide more consistent absorption. The in vitro a...

Prachi Pandeya * and Samarth Kumarb

PHARMACOGNOSTIC STANDARDIZATION OF ANACYCLUS PYRETHRUM LINN AND ITS BIOLOGICAL STUDIES

PAGE 34-40

Despite the long history of traditionally used and clinically potential plant Anacyclus pyrethrum (Akarkara; family – Asteraceae) root parts, the plant has never been investigated systematically for the scientific phytochemical and biological studies till date. Thus, present investigation was e...

Anshu Aroraa , Rakesh Chawlab*, Deepak Kumarc , Sandeep Kumarc , Suraj Bansald, Karamjeet Kaurd and Vijender Kumare

DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF TRANS-RESVERATROL IN ETHOSOMES

PAGE 41-47

The present work describes a simple, accurate and validated UV spectrophotometric method for determination of trans-resveratrol loaded in ethosomal formulation. The method was validated for different parameters like linearity, precision, specificity, accuracy, limit of detection (LOD), limit of q...

Riddhi N. Solankia and Mansi N. Athalyeb*

DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF ELLAGIC ACID AND BERBERINE IN POLYHERBAL FORMULATION BY HPTLC

PAGE 48-53

A rapid, precise, robust, and selective HPTLC technique has been developed for the simultaneous estimation of ellagic acid and berberine from a marketed polyherbal formulation. Chromatographic separation was performed over pre-coated silica gel TLC plates, via a linear ascending technique using t...

Pratiksha S. Morea and Aruna P. Jadhava *

ANTI-ULCER ACTIVITY OF HYDRO-ALCOHOLIC EXTRACT OF SARACA ASOCA STEM BARK IN RATS

PAGE 54-59

In the present study effort has been made to establish the antiulcer activity of Saraca asoca (Roxb.), De Wild (family-Caesalpinaceae) stem bark hydroalcoholic-extract using ethanol induced ulceration model in albino rats, because no systematic study has been reported for its antiulcer activity. ...

Sunita Panchawata , Rupesh K. Gautamb* and Swapnil Goyalc

Short Communications

DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD FOR QUANTITATION OF CLOFARABINE

PAGE 60-63

This experiment aims to develop and validate the RP-HPLC method for clofarabine in a bulk and pharmaceutical dosage form. Chromatographic separation was achieved on Inertsil ODS 3V (150× 4.6 mn) diameter column. The mobile phase comprised of phosphate buffer (pH 4.0): methanol (40:60) at a flow ...

Asif Shirmana *, Gulam J. Khana , Yaasir A. Ansarib, Shoeb Qazia , Z.E. Inamdarb, Hifjurrahman Siddiqib, Umar F. Syedc , Tasqeeruddin Syedd and Shaheen Syedae

APPLICATION OF LIQUISOLID SYSTEMS IN MODIFYING DRUG RELEASE OF GLICLAZIDE

PAGE 64-67

Liquisolid technique is an emerging technology of formulation development. In the present work, a modified-release formulation of gliclazide was developed by using the liquisolid technique. Gliclazide was dispersed in a nonvolatile solvents system of Tween 80 and propylene glycol, followed by ads...

Preha Handaa *, Venkatesh M. Joshib, Ashok K. Sahoob, Sainath Kb, Naganandeshwar Matamb and Nitin Kumarb

Current Issue
August 2022
Quick Contact