Table of Contents

October  2022

  • Volume 59
  • Issue 10
  • Page Nos. 104

Editorial

RESEARCH OPPORTUNITIES ON REPURPOSING FOR ORPHAN DRUG USE

PAGE 5-6

Dear Reader,

The Covid Pandemic had its strong negative impacts and influences. However, the pandemic forced in pharma researchers to work intensively on repurposing of drugs such as Molnupiravir, Baricitinib, Tocilizumab, Ivermectin, Favipiravir, Hydroxychloroquine (HCQ) & chloroquin...

Dr. Gopakumar G. Nair

Editor,

Indian Drugs

Review Article

NANOSTRUCTURED LIPID CARRIERS: A NOVEL STRATEGY FOR TRANSDERMAL DRUG DELIVERY SYSTEMS

PAGE 7-19

Drug administration via the skin is one of the most conventionally used methods where the flux through the skin is the rate-limiting step. Safe carriers are used to provide the anticipated therapeutic effects, which play a vital role in drug delivery. A nanostructured lipid carrier (NLC) is a bin...

Thulasi Sathyanaryanaa and Preethi Sudheera *

Original Research Articles

DESIGN, SYNTHESIS AND EVALUATION OF N-(BENZO[D]THIAZOL-2-YL)-2-OXO2H-CHROMENE-3-CARBOXAMIDE DERIVATIVES AS POTENTIAL ANTIOXIDANT AND ANTIBACTERIAL AGENTS

PAGE 20-29

This research is focused on designing, synthesis and biological evaluation of a series of coumarin based benzothiazole derivatives. The ligands were identified by docking study for antioxidant and antibacterial potential using target proteins PDB:4H1J and PDB:3G75, respectively. The target molecu...

Ranjit V. Gadhavea *, Sachin S. Khadea , Yogita S. Ozardea , Somdatta Y. Chaudharib, Arti G. Swamia and Mukesh K. Meenac

ROLE OF QUALITY BY DESIGN FOR THE OPTIMIZATION OF PUSH PULL OSMOTIC PUMP OF S-METOPROLOL SUCCINATE

PAGE 30-42

The present research was focus on the preparation and evaluation of push pull osmotic pump of S-metoprolol succinate based on Quality by Design (QbD) approaches. For preparation of push pull osmotic pump, pull layer of S-metoprolol succinate was prepared using low molecular weight Polyox by wet g...

Bhupendra G. Prajapatia *, Dipesh V. Patela and Dignesh M. Khuntb

CHARACTERIZATION OF CHEMICAL COMPOUNDS OF MEDICINAL IMPORTANCE IN DIOSPYROS MONTANA ROXB.

PAGE 43-56

Plants and their constituents are precious gift of nature to the humans being. They fulfill various routine requirements of human being including the most important health care issues. The aim of the present study is to investigate the bioactive compounds in leaf, stem and seeds of Diospyros mont...

Anita Kumaria * and Malkiat C. Sidhua

DIFFUSE REFLECTANCE FOURIER TRANSFORM INFRARED SPECTROSCOPIC QUANTIFICATION OF TWO NOVEL DRUGS IN PHARMACEUTICALS: A NEW CASE STUDY FOR CHEMOMETRICS ASSISTED ANALYTICAL PROCEDURE DEVELOPMENT APPROACH

PAGE 57-65

Two robust and scientifically sound diffuse reflectance Fourier transform infrared spectroscopic methods were developed for quantitative estimation of two novel drugs, capecitabine and cinacalcet hydrochloride, in drug substance and tablet dosage forms. Influence of method variables was investiga...

Sagar S. Pandaa * and Ravi Kumar V.V.Beraa

VALIDATED RP-HPLC METHOD AND STABILITY STUDIES FOR SIMULTANEOUS ESTIMATION OF OFLOXACIN AND RACECADOTRIL IN BULK AND PHARMACEUTICAL FORMULATION

PAGE 66-73

A simple, accurate and precise stability indicating method for simultaneous estimation of ofloxacin and racecadotril in bulk and marketed formulation was developed and validated by RP-HPLC. The chromatographic separation of this method was carried out by Waters X Bridge Stainless steel C18 column...

Yunes M. M. Ali Alsayadia and Pooja A. Chawlaa *

STABILITY INDICATING HPLC METHOD FOR SOFOSBUVIR AND DACLATASVIR IN COMBINATION

PAGE 74-79

Direct acting fixed dose combination of sofosbuvir and daclatasvir to treat the viral hepatitis C disease is available in the market. So, a precise and robust stability indicating HPLC method for sofosbuvir and daclatasvir was developed. The SunQ C18 column (250 x 4.6 mm) was used for chromatogra...

Mrinalini C. Damlea * and Nivedita B. Pawara

MEGAMOX MEDIATES ECO-FRIENDLY SYNTHESIS OF SELENIUM NANOPARTICLES AS IMMUNOMODULATORY, ANTIOXIDANT AND ANTIMICROBIAL AGENTS

PAGE 80-90

The research herein includes methodology for eco-friendly preparation of selenium nanoparticles (SeNPs) using the broad-spectrum antibiotic, Megamox (Mega.). Characterization of SeNPs was done using UV-Visible spectroscopy, FTIR, XRD, DLS and TEM imaging. Additionally, the immunomodulatory, antio...

Ahmed A. Askara , Asmaa M. Abouzaidb, Akhilesh Dubeyc * and Sally A. El-Zahabyd

Short Communications

TOPICAL DELIVERY OF EXTRACTIVE PHYTOCONSTITUENTS OF SOYABEAN SEEDS FOR MANAGEMENT OF PSORIASIS

PAGE 91-94

The aim of the present study was to evaluate antipsoriatic activity of extractive phytoconstituents of the seeds of Glycine max (soyabean). Oxidative stress is considered as one of the important etiopathological factors in development and exacerbation of psoriasis. Isoflavones, the most important...

Sania K. Khana , Niserga D. Sawanta , Prachi C. Mehendalea and Namita D. Desaia *

PATTERN OF PRESCRIPTIONS IN COMMUNITY PHARMACIES – A CROSS SECTIONAL STUDY

PAGE 95-98

Medication error is a worldwide public health issue which most commonly arises due to prescription errors. Objective of this study was to conduct a retrospective cross-sectional study of prescription patterns in community pharmacies in random regions of the states Maharashtra and Bihar. This stud...

Karishma M. Rathia , Harshad S. Kapareb*, Snehal D. Dherangea and Aanya S. Vermaa

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