Table of Contents

February  2022

  • Volume 59
  • Issue 2
  • Page Nos. 76

Editorial

JAN AUSHADHI – MEDICINES FOR THE MASSES*

PAGE 5-6

Dear Reader,

Universal health care is a goal which most nations are striving to achieve. Brazil can boast of showing the way – it is perhaps the only country today where any individual within Brazilian jurisdiction is deemed eligible to receive free, instant and complete healthcare with...

Dr. Nagaraj Rao

Associate Editor

Indian Drugs

Review Article

LEAD PHYTOMOLECULES FOR HEPATOPROTECTIVE DRUG DEVELOPMENT

PAGE 7-26

Plants are the precious gift of nature to mankind and play a major role in the treatment of various diseased conditons from the ancient times. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatme...

Krishn K. Agrawala and Yogesh Murtib*

Original Research Articles

DESIGN, SYNTHESIS AND EVALUATION OF NOVEL AZETIDINONYL/ FORMAZONYL/ THIAZOLIDINONYLPHENOTHIAZINES AS POTENTIAL ANTI-INFLAMMATORY AGENTS

PAGE 27-35

The present study describes the synthesis, full characterization and biological evaluation of novel azetidinonyl/formazonyl/thiazolidinonylphenothiazines. The synthesis of these compounds as potential anti-inflammatory agents was carried out using a more efficient and versatile synthetic route. V...

Archanaa *, Sakshi Chaudharyb and Nancya

ANALYTICAL STANDARDIZATION AND PROFILING OF AYUSH-64: AN AYURVEDIC TABLET FORMULATION

PAGE 36-42

Success of any healthcare product is based on its performance, which is further dependent upon the quality of the product. Quality of the polyherbal ayurvedic formulation is assured by developing proper analytical standards with the help of the guidelines provided by CCRAS (Central Council for Re...

Sarang J. Deshpandea , Prakash N. Kendreb* and Abhishek R. Patlec

EVALUATION OF RADICAL SCAVENGING ACTIVITY AND PROLIFERATIVE ACTIVITY OF HERBAL DECOCTION ON CULTURED CARDIAC CELLS

PAGE 43-46

Stem cell research is being pursued in the hope of achieving major medical breakthroughs in treatment of diseases. Experiments over several years have purported to show that stem cells have a phenomenon known as plasticity which includes blood cells becoming neurons and liver cells that can be ma...

Mangalagowri A.a * and Priya S.b

ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF A NOVEL HPTLC (METHOD) FOR THE SIMULTANEOUS ESTIMATION OF BERBERINE, GALLIC ACID, QUERCETIN AND PIPERINE IN A POLYHERBAL FORMULATION

PAGE 47-51

A novel, accurate, precise High Performance Thin Layer Chromatography (HPTLC) method for the simultaneous estimation of berberine, gallic acid, quercetin and piperine in a polyherbal formulation has been developed and validated as per ICH guidelines. A good chromatographic separation was achieved...

Shivani A. Vaidyaa , Rishikesh R. Kshirsagara , Kirti S. Laddhab and Vandana N. Jaina *

SIMULTANEOUS ESTIMATION OF IMPURITIES IN MELATONIN BY RP-HPLC METHOD COUPLED WITH DIODE ARRAY DETECTION

PAGE 52-57

In the present research work, RP-HPLC method coupled with diode array detection for separation and quantitation of impurity-I (2-(5-methoxy-1H-indol-3-yl)ethanamine), impurity-II (3-(2-aminoethyl)- 1H-indol-5-ol) along with melatonin was developed. Mobile phase containing 10 mMolL-1 sodium dihydr...

Shubhangi Sutara *, Veerendra Yeligarb, Prafulla Choudharic and Sachinkumar Patila

MICROBIOLOGICAL AND ANTIBIOGRAM STUDY OF BACTERIAL PATHOGENS ASSOCIATED WITH BOVINE MASTITIS IN AND AROUND MEERUT

PAGE 58-63

A rise in the incidence of disease in a herd results in multiplied use of antimicrobials, which in turn increases the presence of antibiotic residues in milk and increased bacterial resistance to antimicrobials. Continued use of antibiotics in the remedy and prevention of diseases of dairy cows a...

Harshit Vermaa *, Amit Kumarb, Prabhat Kumarb, Surendra Upadhyayb, Anamika Bhordiab and Jitender Singhb

Short Communications

STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION OF MEROPENEM AND VABORBACTAM IN PHARMACEUTICAL DOSAGE FORM

PAGE 64-67

A simple, novel, rapid, accurate and precise stability indicating RP-HPLC method was developed and validated for simultaneous estimation of meropenem and vaborbactum in pharmaceutical dosage form. Meropenem an antibacterial, and vaborbactam, a beta-lactamase inhibitor are indicated for the treatm...

Prasanthi T.a *, Lakshmana Rao A.a and Mohana Rao B.a

MICROSPHERE AND TABLET IN CAPSULE SYSTEM: A NOVEL CHRONOTHERAPEUTIC SYSTEM OF DICLOFENAC SODIUM FOR SITE AND TIME SPECIFIC DELIVERY

PAGE 68-70

The objective of the present study is to develop and evaluate microsphere and tablet in capsule system for the treatment of rheumatoid arthritis as a dual pulse release system. The capsule system contains enteric coated cap filled with microspheres (sustained release) that lock the impermeable ca...

Lalita Palariyaa , Sweta Bawaria and Archana N. Saha*

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