Table of Contents

March  2013

  • Volume 50
  • Issue 3
  • Page Nos. 1-60

Review Article

Melt Granulation: An Alternative to Traditional Granulation Techniques

PAGE 5-13

Melt granulation is a size enlargement process in which the addition of a binder that melts or softens at relatively low temperatures (about 60C) is used to achieve agglomeration of solid particles in the formulation. The process utilizes materials that ...

Desai U.S.*, Chaudhari P.D., Bhavsar D.B. and Chavan R.P.

Original Research Articles

Effectiveness of Microwave Drying in Improving Granule Characteristics in Tablets

PAGE 14-19

In the present study, metformin hydrochloride is used as model drug and the granules were formed by using tray drying and microwave technique. The granules prepared by microwave technique and tray dryer technique are evaluated for parameters such as amount of fines, d...

Tarkase K. N.*, Tarkase M. K., Deshpande A. P., Wagh V. S. and Dokhe M. D.

Development and Validation of Uv Spectrophotometric Method for Estimation of Prochlorperazine Maleate and Pyridoxine Hydrochloride in Tablet Dosage Form by Uv Using Multi-Component Mode of Analysis

PAGE 20-25

Prochlorperazine maleate and pyridoxine hydrochloride in combination are available as tablet dosage forms in the ratio of 1:5. A simple, reproducible and efficient method for the simultaneous determination of prochlorperazine maleate and pyridoxine hydrochloride in ta...

Bhagwat G. B.*, Wate S. P. and Mundhey A. S.

A Simple and Rapid Hplc Method for Estimation of Dimethicone from Formulations

PAGE 26-29

A simple, sensitive, precise and specific normal phase high performance liquid chromatography (HPLC) method was developed and validated for the determination of dimethicone from tablet dosage forms. It was found that the excipients used in the tablet dosage form did n...

Jadhav J. J.*, Mungekar S., Velada J. V., Doshi H. A. , Gajbe V. and Raunak K.

Simultaneous Estimation of Montelukast Sodium and Desloratadine in Bulk and in Tablet Formulation by Uv-Spectophotometry

PAGE 30-35

Novel, simple, sensitive and rapid spectrophotometric method has been developed for simultaneous estimation of montelukast sodium (MONTE) and desloratadine (DES). The method involved solving simultaneous equations based on measurement of absorbance at two wavelengths ...

Jain R. R., Patil P. O.* and Bari S. B.

Anti Atherosclerotic Effect of Ethanolic Stem Extract of Cissus Quadrangularis Linn

PAGE 36-45

Atherosclerosis and the subsequent complications cause many deaths world wide. Though many medications like statins and surgical procedures are available to tackle this problem, none of them is hazard free. In the present study the ethanolic extract of the plant C...

Soumya V.S., and Dominic S.*

Short Notes

Immunomodulatory Activity of Methanolic Extracts of Seeds and Bark of Pongamia Glabra Vent. on Human Neutrophils

PAGE 46-52

Methanolic extracts of seeds and bark of Pongamia glabra Vent. (250 mg/kg and 500 mg/kg p.o.) in the concentration range 100, 50, 25, 12 and 6.25 µg were subjected to evaluate the phagocytic effect on human neutrophils using the in-vitro models – ...

Heroor S.S.*, Beknal A.V. and Mahurkar N.K.

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