Articles Accepted

Objective(s): Determination of toxic, genotoxic and cytotoxic effects of Drosophila melanogaster for M. fistulosa var. menthifolia, M. fistulosa, M. didyma and M. media. Materials and methods: The Oregon-R line was used to test for toxic manifestations in a number of indicators: fecundity, early and late embryonic mortality of offspring, total lethality of individuals (LC50). The genotoxic effect was recorded using SMART. The change in the wing shape and regulated cell death was determined. Results: The lethality of individuals grown on a nutrient medium with the addition of an extract of M. fistulosa var. menthifolia, as well as F1 offsprings at the embryonic stage of development. Genotoxicity was not registered for any of the tested extracts. The M. didyma extract is characterized by cytotoxic properties. Conclusions: An effect on viability was found for extracts of M. media and M. fistulosa var. menthifolia. Cytotoxic effect was observed when exposed to M. didyma extract.