Articles Accepted

Anti-hemorrhoidal activity of Ayurvedic medicine, Piloheal cream in rats
by Dr. Anil Pawar, 23 Jan 2017

Piloheal cream is an Ayurvedic proprietary medicine claimed to be effective in the treatment of hemorrhoids. The present work was undertaken to evaluate the antihemorrhoidal activity of Piloheal cream against croton oil-induced hemorrhoids in rats. The hemorrhoids were induced by applying 3% croton oil preparation in the ano-rectal region. Rats were intrarectally administered with Piloheal cream, twice a day for 4 days. Hemorrhoids were assessed by measuring macroscopic parameters such as weight, area of mucosal damage and number of red thrombus of ano-rectal tissue along with histology of the tissue. Croton oil application induced hemorrhoids as indicated by increase in weight, area of mucosal damage and number of red thrombus of ano-rectal tissue along with marked histological damage as compared to normal rats. Treatment with Piloheal prevented the elevation of macroscopic and histological changes. Piloheal treatment showed significant anti-hemorrhoidal activity against croton oil-induced hemorrhoids in rats.

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