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Industry can look forward to work with CSIR-CDRI in this new era of dynamic leadership of CSIR, with Dr. (Mrs) N. Kalaiselvi, the new Director General of CSIR and Secretary, DSIR and Dr. (Mrs) Radha Rangarajan, Director, CDRI, Lucknow, who has recently taken charge of this pi...

Bioanalytical methods are used to analyse an analyte in a biological matrix. Bioanalytical method validation is the process of determining the suitability of the given bioanalytical methodology for providing the required analytical data. Validation of the bioanalytical methods demonstrates and en...

In the present work, a facile, eco-friendly, and cost-effective approach is described to remove Cr3+ toxic metal ions in an aqueous solution by nickel nanoparticles (NiNPs) synthesized via a green method utilizing Sterculia foetida leaf extract. The synthesized nickel nanoparticles were character...

The development of an in situ metronidazole gel that is mucoadhesive and thermo sensitive was the aim of this study in the fight against bacterial vaginosis. Numerous evaluation criteria have been carried out, including mucoadhesive force, pH, viscosity, syringe capability, medication content, ge...

Acmella oleracea flowers are traditionally used to treat mouth ulcers in the rural areas of Nashik, Maharashtra, India. This research project is an effort to understand the scientific basis for the utility of A. oleracea flowers and validate it for potential antimicrobial, anti-inflammatory and a...

The aim of the present work was to investigate degradation behavior of tavaborole upon exposure to oxidative conditions using first order derivative UV spectrophotometric method. We have developed simple and fast analytical method that can be used as quality control tool for the determination of ...

A novel bioanalytical LC-MS/MS method for irbesartan and hydrochlorothiazide has been developed using deuterated internal standards. Sample pretreatment was carried out using Strata-X Cartridge 33µm. Chromatographic separation was achieved on Chromolith® High Resolution Column, 100X4.6mm, 5µ u...

For the purpose of analyzing empagliflozin, a stability indicating high performance thin layer chromatographic method was developed. This method was optimized using design of experiment. In order to optimize the process, independent variables such as the proportion of isopropyl alcohol in the mob...

Thyme essential oil (TEO) is a prominent essential oil reported to have diverse properties and biological activities including anti-inflammatory. This research aims to encapsulate TEO in prepared microsponges for the purpose of controlled drug delivery and reduce the frequency of drug administrat...

This research work’s motive was to investigate the superfluity potential of the BCS-II drug (Dextromethorphan HBr) by solvent shift method to evaluate the impact of polymer gain factor on superfluity potential for the enhancement of bioavailability of orally prolonged release. To maintain the s...

For arthritis, there is need of development of a drug delivery system which permits less frequent dosing by maintaining a close contact with the skin for prolonged time period, thereby improving the patient compliance, especially among elderly. Till date, film forming gels of aceclofenac for arth...

The pods of Acacia nilotica L. are traditionally used for versatile medical applications and are rich in polyphenolics and flavonoids. The pods powder is available in the market either as branded or unbranded products and it is imperative that their quality be assessed by a valid analytical metho...