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Although the COVID-19 pandemic is still a huge cause for worry for governments and populations like, a new threat is raising its head across various countries in the form of monkeypox. Till date, more than 5000 monkeypox cases have been reported from 51 countries worldwide. H...
Cancer refers to a group of illnesses that result from cell population in the body increasing unusually. These cells break up and create new cells in an uninhibited mode that can extend in the body and cause injury to vital organs. Analytical chemistry is the division of chemistry involved in sep...
A new series of quinoline derivatives has been synthesized by two different methods. In the first methods, 6-subtituted 2-(pyridin-3/4-yloxy) quinoline-3-carbaldehyde 2 was reduced with NaBH4 in methanol and then reacted with thionylchloride in DMC to give 3 which on chloramines coupling with 1,3...
A combination of proteolytic enzyme pepsin with amylolytic α- amylase serves as an ideal digestive enzyme supplement for the treatment of functional dyspepsia and exocrine pancreatic insufficiency. In the present research work, an attempt was made to develop a release modulated formulation which...
There has been a tremendous increase in the demand for plant-based drugs over the last several years. Due to this, there is a need for standardization of the plant raw materials. Although modern techniques are being widely used for the standardization process, the pharmacognostic approach is stil...
A new, simple and rapid high-performance thin-layer chromatographic method was developed and validated for quantitative determination of hydrochlorothiazide and lisinopril. Both the drugs were chromatographed on silica gel 60 F254 HPTLC plate using chloroform: methanol: ethyl acetate: acetic acid...
The present study was aimed to develop a novel, simple, rapid, accurate, stability-indicating ReversedPhase High-Performance Liquid Chromatography method and its validation for the simultaneous estimation of vortioxetin and aripiprazole in synthetic mixture. RP-HPLC method was carried out by isoc...
The aim of the present study was to evaluate the sedative and anxiolytic property of the leaves of the Dolichandrone atrovirens (D. atrovirens) The chloroform and ethanolic extracts of leaves were analysed for their phytochemical constituents by phytochemical screening and thin layer chromatograp...
“Raktachandan” or Pterocarpus santalinus was identified as indigenous to Eastern Ghats of India. This ethnopharmacological drug has been used since ages as a colouring material. It is mentioned in Charaka Samhita, which is a sacred treatise based on the Indian system of medicine, “Ayurveda...
This research work deals with formulation of mouthwash containing Mimusops elengi fruit saponins and studying in vitro antimicrobial activity against dental pathogens isolated from patients suffering from dental problems. In this study, saponins were isolated from the crude unripe fruit powder an...