Table of Contents

June  2022

  • Volume 59
  • Issue 6
  • Page Nos. 80

Editorial

MONKEYPOX

PAGE 5-6

Dear Reader,

Although the COVID-19 pandemic is still a huge cause for worry for governments and populations like, a new threat is raising its head across various countries in the form of monkeypox. Till date, more than 5000 monkeypox cases have been reported from 51 countries worldwide. H...

Dr. Nagaraj Rao

Associate Editor

Indian Drugs

Review Article

VERSATILE APPROACHES FOR ANALYTICAL METHOD VALIDATION OF ANTICANCER DRUGS: A REVIEW

PAGE 7-22

Cancer refers to a group of illnesses that result from cell population in the body increasing unusually. These cells break up and create new cells in an uninhibited mode that can extend in the body and cause injury to vital organs. Analytical chemistry is the division of chemistry involved in sep...

Himani Kanwara , Swati Pandeyb, Ravindra K. Pandeyc and Shiv S. Shuklaa *

Original Research Articles

BIOLOGICAL ACTIVITY AND DRUG LIKE SCORE OF NEW SYNTHESIZED QUINOLINE DERIVATIVES INCORPORATED WITH PYRIDINE AND 1,3,4 - THIADIAZOLE MOIETY

PAGE 23-29

A new series of quinoline derivatives has been synthesized by two different methods. In the first methods, 6-subtituted 2-(pyridin-3/4-yloxy) quinoline-3-carbaldehyde 2 was reduced with NaBH4 in methanol and then reacted with thionylchloride in DMC to give 3 which on chloramines coupling with 1,3...

Ankit J. Patela *, Manish P. Patela , Amitkumar B. Dholakiaa , Vishant C. Patela and Darshan S. Patela

RELEASE MODULATED DELIVERY OF DIGESTIVE ENZYME SUPPLEMENT

PAGE 30-36

A combination of proteolytic enzyme pepsin with amylolytic α- amylase serves as an ideal digestive enzyme supplement for the treatment of functional dyspepsia and exocrine pancreatic insufficiency. In the present research work, an attempt was made to develop a release modulated formulation which...

Pooja S. Lawandea , Sandesh N. Somnachea *, Ajeet M. Godbolea , Pankaj S. Gajarea and Arti S. Pednekara

PHARMACOGNOSTIC STUDIES ON LEAVES OF GYMNANTHEMUM AMYGDALINUM WITH SPECIAL REFERENCE TO A NEW ADDITION TO THE FLORA OF SOUTH INDIA

PAGE 37-46

There has been a tremendous increase in the demand for plant-based drugs over the last several years. Due to this, there is a need for standardization of the plant raw materials. Although modern techniques are being widely used for the standardization process, the pharmacognostic approach is stil...

Prabhakar Gajulaa *, Kamalakar Palakurthyb and Shailaja Kusumab

A NOVEL VALIDATED STABILITY INDICATING ANALYTICAL HPTLC METHOD FOR QUANTITATION OF HYDROCHLOROTHIAZIDE AND LISINOPRIL IN TABLET FORMULATION

PAGE 47-51

A new, simple and rapid high-performance thin-layer chromatographic method was developed and validated for quantitative determination of hydrochlorothiazide and lisinopril. Both the drugs were chromatographed on silica gel 60 F254 HPTLC plate using chloroform: methanol: ethyl acetate: acetic acid...

Rashmin B. Patela * and Mrunali R. Patelb

NEW RP-HPLC METHOD FOR DETERMINATION OF VORTIOXETINE AND ARIPIPRAZOLE IN SYNTHETIC MIXTURE

PAGE 52-59

The present study was aimed to develop a novel, simple, rapid, accurate, stability-indicating ReversedPhase High-Performance Liquid Chromatography method and its validation for the simultaneous estimation of vortioxetin and aripiprazole in synthetic mixture. RP-HPLC method was carried out by isoc...

Suresh Kumara *, Ancy Mathewb and Dhara Vashib

NEUROPHARMACOLOGICAL ACTIVITY OF DOLICHANDRONE ATROVIRENS (ROTH) LEAF EXTRACTS IN SWISS ALBINO MICE

PAGE 60-66

The aim of the present study was to evaluate the sedative and anxiolytic property of the leaves of the Dolichandrone atrovirens (D. atrovirens) The chloroform and ethanolic extracts of leaves were analysed for their phytochemical constituents by phytochemical screening and thin layer chromatograp...

Sankar V.a , Baby Roselin R.a *, Arjunan K.a , Thirupathy Kumaresan P.b and Abdul Khayum K.b

Short Communications

AUGMENTATION OF AESTHETIC AND ANTISOLAR ATTRIBUTES OF A SUNSCREEN CREAM BY METHANOLIC EXTRACT OF RAKTCHANDAN (PTEROCARPUS SANTALINUS)

PAGE 67-70

“Raktachandan” or Pterocarpus santalinus was identified as indigenous to Eastern Ghats of India. This ethnopharmacological drug has been used since ages as a colouring material. It is mentioned in Charaka Samhita, which is a sacred treatise based on the Indian system of medicine, “Ayurveda...

Sanju Nandaa and Kumud Madanb*

ANTIBACTERIAL ACTIVITY OF MOUTHWASH CONTAINING MIMUSOPS ELENGI LINN FRUIT SAPONINS AGAINST DENTAL PATHOGENS

PAGE 71-74

This research work deals with formulation of mouthwash containing Mimusops elengi fruit saponins and studying in vitro antimicrobial activity against dental pathogens isolated from patients suffering from dental problems. In this study, saponins were isolated from the crude unripe fruit powder an...

Aparna Palshetkar D.a and Pratima Tatke A.b*

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